Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GRN | P28799 | 1/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12746805 | 0.86 | KDM4E (0.42) | MAPK14KDM4EGRNSORT1MAPT | |
| SCHEMBL12746844 | 0.76 | CNR2 (0.48) | MAPK14KDM4EGRNSORT1MAPT | |
| SCHEMBL7112019 | 0.76 | MAPK14 (0.63) | MAPK14KDM4EGRNSORT1MAPT | |
| SCHEMBL10146074 | 0.75 | KDM4E (0.42) | MAPK14KDM4EGRNSORT1MAPT | |
| SCHEMBL10147819 | 0.75 | KDM4E (0.42) | MAPK14KDM4EGRNSORT1MAPT | |
| SCHEMBL12824743 | 0.74 | CNR2 (0.40) | MAPK14KDM4EGRNSORT1MAPT | |
| SCHEMBL12747060 | 0.74 | KDM4E (0.41) | MAPK14KDM4EGRNSORT1MAPT | |
| SCHEMBL13618716 | 0.71 | KDM4E (0.40) | MAPK14KDM4EGRNSORT1MAPT | |
| SCHEMBL1699062 | 0.68 | MAPK14 (0.61) | MAPK14KDM4EGRNSORT1MAPT | |
| SCHEMBL10146096 | 0.66 | KDM4E (0.39) | MAPK14KDM4EGRNSORT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011037795-A1 | COMPOUNDS WHICH SELECTIVELY MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-31 | — | — | WO | disclosed |