⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluciclovine F18 SCHEMBL10017245 | 1.00 | — | — | |
| Fluciclovine F18 SCHEMBL11939900 | 1.00 | — | — | |
| Fluciclovine SCHEMBL5934962 | 1.00 | — | — | |
| Fluciclovine F18 SCHEMBL11939897 | 1.00 | — | — | |
| Fluciclovine F18 SCHEMBL1449765 | 1.00 | — | — | |
| SCHEMBL25492080 | 0.84 | GRM4 (0.58) | — | |
| SCHEMBL25492075 | 0.84 | GRM4 (0.58) | — | |
| SCHEMBL23833793 | 0.84 | GRM4 (0.58) | — | |
| SCHEMBL25492047 | 0.84 | GRM4 (0.58) | — | |
| SCHEMBL30198807 | 0.84 | GRM4 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11077216-B2 | Formulation and method of synthesis | GE HEALTHCARE LIMITED (GB) | 2021-08-03 | — | — | US | disclosed |
| US-9999692-B2 | Radiolabelling process | GE HEALTHCARE LIMITED (GB) | 2018-06-19 | — | — | US | disclosed |
| US-7910745-B2 | Organic compound and method for producing radioactive halogen-labeled organic compound using the same | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2011-03-22 | — | — | US | disclosed |
| US-20090105489-A1 | NOVEL ORGANIC COMPOUND AND METHOD FOR PRODUCING RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND USING THE SAME | NIHON MEDI-PHYSICS CO. LTD. (JP) | 2009-04-23 | — | — | US | disclosed |
| EP-1889834-A1 | NOVEL ORGANIC COMPOUND AND METHOD FOR PRODUCING RADIOACTIVE HALOGEN-LABELED ORGANIC COMPOUND USING THE SAME | Nihon Medi-Physics Co., Ltd. (JP) | 2008-02-20 | — | — | EP | disclosed |