Fluciclovine

Fluciclovine

SCHEMBL5934962

N[C@]1(C(=O)O)C[C@@H](F)C1

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluciclovine F18 SCHEMBL10017245 1.00 — —
Fluciclovine F18 SCHEMBL12824573 1.00 — —
Fluciclovine F18 SCHEMBL11939900 1.00 — —
Fluciclovine F18 SCHEMBL11939897 1.00 — —
Fluciclovine F18 SCHEMBL1449765 1.00 — —
SCHEMBL25492080 0.84 GRM4 (0.58) —
SCHEMBL25492075 0.84 GRM4 (0.58) —
SCHEMBL23833793 0.84 GRM4 (0.58) —
SCHEMBL25492047 0.84 GRM4 (0.58) —
SCHEMBL30198807 0.84 GRM4 (0.58) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12502554-B2 Methods for radiation delivery in emission-guided radiotherapy REFLEXION MEDICAL, INC. (US) 2025-12-23 — — US claimed
WO-2025226286-A1 SYSTEMS AND METHODS FOR SIMULTANEOUS IMAGING OF MULTIPLE POSITRON EMISSION TOMOGRAPHY (PET) TRACERS MULTIF UNCTIONAL IMAGING LLC (US) 2025-10-30 — — WO claimed
US-20250329024-A1 SYSTEMS AND METHODS FOR SIMULTANEOUS IMAGING OF MULTIPLE POSITRON EMISSION TOMOGRAPHY (PET) TRACERS MultiFunctional Imaging LLC (US) 2025-10-23 — — US claimed
CN-118662796-A Systems and methods for bio-adaptive radiation therapy 反射医疗公司 2024-09-20 — — CN claimed
US-20240299598-A1 METHODS FOR DETECTING CCR2 RECEPTORS WASHINGTON UNIVERSITY (US) 2024-09-12 — — US claimed
US-12086990-B1 Systems and methods for simultaneous imaging of multiple positron emission tomography (PET) tracers MultiFunctional Imaging LLC (US) 2024-09-10 — — US claimed
US-12016935-B2 Methods for detecting CCR2 receptors WASHINGTON UNIVERSITY (US) 2024-06-25 — — US claimed
EP-4344736-A2 METHODS FOR CALCULATING BOUNDED DOSE-VOLUME HISTOGRAMS (DVH) FOR EVALUATING A TREATMENT PLAN RefleXion Medical, Inc. (US) 2024-04-03 — — EP claimed
US-11896417-B2 Time-varying kinetic modeling of high temporal-resolution dynamic pet data for multiparametric imaging THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-02-13 — — US claimed
US-11648418-B2 Systems and methods for biological adaptive radiotherapy REFLEXION MEDICAL, INC. (US) 2023-05-16 — — US claimed
US-20230067048-A1 METHODS FOR RADIATION DELIVERY IN EMISSION-GUIDED RADIOTHERAPY REFLEXION MEDICAL, INC. 2023-03-02 — — US claimed
US-20260137789-A1 BRUSH PRODRUGS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2026-05-21 — — US disclosed
US-20260137765-A1 METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF INSTITUT CURIE (FR) 2026-05-21 — — US disclosed
WO-2026104860-A2 ACTIVATABLE BINDING MOLECULE CAMBRIDGE ENTERPRISE LIMITED (GB) 2026-05-21 — — WO disclosed
EP-4727601-A1 IMPROVED SYNTHESIS OF THE PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) RADIOLABELED INHIBITOR [18F]DCFPYL Progenics Pharmaceuticals, Inc. (US) 2026-04-22 — — EP disclosed
WO-2022029294-A1 PET-CT IMAGING METHODS, CONTRAST AGENTS AND PHARMACEUTICAL COMPOSITIONS FOR USE IN SAID IMAGING METHODS ADIPOSS SÁRL (CH) 2022-02-10 — — WO disclosed
WO-2019027033-A1 LIVER CANCER IMAGING BY Fluciclovine 日本メジフィジックス株式会社 2019-02-07 — — WO disclosed
US-20170128597-A1 NOVEL FORMULATION AND METHOD OF SYNTHESIS GE HEALTHCARE LIMITED (GB) 2017-05-11 — — US disclosed
WO-2011006621-A1 RADIOLABELLING METHOD USING CYCLOALKYL GROUPS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2011-01-20 — — WO disclosed
US-20060292073-A1 Stereoselective Synthesis of Amino Acid Analogs for Tumor Imaging EMORY UNIVERSITY (US) 2006-12-28 — — US disclosed
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