Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10003705 | 0.92 | SMO (0.39) | SMOKMT2ATSHRMAPTEPHX2 | |
| SCHEMBL10003025 | 0.87 | SMO (0.43) | SMOKMT2AALDH1A1TP53TSHR | |
| SCHEMBL10003483 | 0.87 | SMO (0.57) | SMOKMT2AEPHX2MEN1 | |
| SCHEMBL10003179 | 0.84 | SMO (0.44) | SMOKMT2AALDH1A1EPHX2MEN1 | |
| SCHEMBL10003363 | 0.81 | SMO (0.52) | SMOKMT2AALDH1A1TSHREPHX2 | |
| SCHEMBL16588414 | 0.81 | SMO (0.50) | SMOKMT2AEPHX2MEN1 | |
| SCHEMBL10003768 | 0.81 | SMO (0.49) | SMOEPHX2 | |
| SCHEMBL10003194 | 0.81 | SMO (0.40) | SMOKMT2ATSHREPHX2HTR1A | |
| SCHEMBL16070729 | 0.79 | SMO (0.48) | SMOKMT2AMAPTEPHX2MEN1 | |
| SCHEMBL10003951 | 0.79 | SMO (0.49) | SMOKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011024869-A1 | FUSED HETEROCYCLIC RING DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2011-03-03 | — | — | WO | disclosed |