Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.61 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.61 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.61 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL256211 | 0.78 | PI4KA (0.63) | PI4KAPI4K2BPI4K2API4KBKDM4E | |
| SCHEMBL25605061 | 0.76 | PI4KA (0.61) | PI4KAPI4K2BPI4K2API4KBKDM4E | |
| SCHEMBL13510 | 0.76 | PI4KA (0.61) | PI4KAPI4K2BPI4K2API4KBKDM4E | |
| SCHEMBL4379601 | 0.76 | PI4KA (0.61) | PI4KAPI4K2BPI4K2API4KBKDM4E | |
| SCHEMBL2822778 | 0.74 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBKDM4E | |
| SCHEMBL31175304 | 0.74 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBKDM4E | |
| SCHEMBL20276307 | 0.73 | PI4KA (0.58) | PI4KAPI4K2BPI4K2API4KBKDM4E | |
| SCHEMBL21851658 | 0.73 | ALDH1A1 (0.58) | PI4KAPI4K2BPI4K2API4KBKDM4E | |
| SCHEMBL21348442 | 0.73 | SMN1; SMN2 (0.58) | PI4KAPI4K2BPI4K2API4KBKDM4E | |
| SCHEMBL12766976 | 0.73 | PI4KA (0.58) | PI4KAPI4K2BPI4K2API4KBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023081-A1 | 5,6-BICYCLIC HETEROARYL-CONTAINING UREA COMPOUNDS AS KINASE INHIBITORS | ASCEPION PHARMACEUTICALS, INC. (CN) | 2011-03-03 | — | — | WO | disclosed |