Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | BPTF | Q12830 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10366469 | 0.87 | GAA (0.50) | GAAKMT2AALDH1A1NPBWR1MCHR1 | |
| SCHEMBL981480 | 0.85 | KMT2A (0.54) | GAAKMT2AALDH1A1NPBWR1MCHR1 | |
| SCHEMBL27673286 | 0.82 | GAA (0.46) | GAAKMT2ANR2E3ALDH1A1NPBWR1 | |
| SCHEMBL20995545 | 0.81 | ATM (0.49) | GAANR2E3ALDH1A1NPBWR1MCHR1 | |
| SCHEMBL27673287 | 0.81 | GAA (0.45) | GAAKMT2AALDH1A1NPBWR1MCHR1 | |
| SCHEMBL10368114 | 0.80 | GAA (0.44) | GAAKMT2AALDH1A1NPBWR1MCHR1 | |
| SCHEMBL10858045 | 0.78 | BRD4 (0.44) | GAAKMT2ANR2E3ALDH1A1NPBWR1 | |
| SCHEMBL16998536 | 0.78 | SMN1; SMN2 (0.53) | GAAKMT2ANR2E3ALDH1A1NPBWR1 | |
| SCHEMBL10616008 | 0.77 | BRD4 (0.43) | GAAKMT2ANR2E3ALDH1A1NPBWR1 | |
| SCHEMBL15885153 | 0.77 | NR2E3 (0.55) | GAAKMT2ANR2E3ALDH1A1NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011028492-A2 | SORTASE A INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-03-10 | — | — | WO | disclosed |