Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BPTF | Q12830 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12826267 | 0.87 | GAA (0.53) | GAAKMT2ABRD4BPTFKAT2B | |
| SCHEMBL981480 | 0.82 | KMT2A (0.54) | GAAKMT2ABRD4BPTFKAT2B | |
| SCHEMBL27673286 | 0.80 | GAA (0.46) | GAAKMT2ABRD4BPTFKAT2B | |
| SCHEMBL10366104 | 0.79 | SMN1; SMN2 (0.51) | GAAKMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL10367542 | 0.79 | BPTF (0.42) | GAABPTFKAT2BALDH1A1SMN1; SMN2 | |
| SCHEMBL27673287 | 0.79 | GAA (0.45) | GAAKMT2ABRD4BPTFKAT2B | |
| SCHEMBL10368114 | 0.77 | GAA (0.44) | GAAKMT2ABRD4BPTFKAT2B | |
| SCHEMBL10681093 | 0.76 | ALDH1A1 (0.48) | KMT2AALDH1A1HTTSMN1; SMN2NPBWR1 | |
| SCHEMBL10858045 | 0.76 | BRD4 (0.44) | GAAKMT2ABRD4BPTFKAT2B | |
| SCHEMBL10690664 | 0.75 | PPARD (0.43) | GAAKMT2ABRD4BPTFMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0193853-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |
| US-4783462-A | 3(2H)pyridazinone, and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-11-08 | — | — | US | disclosed |
| EP-0193853-A2 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-09-10 | — | — | EP | disclosed |