Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1282705 | 1.00 | TP53 (0.35) | TP53ALDH1A1TSHR | |
| SCHEMBL29112562 | 0.82 | ALDH1A1 (0.36) | TP53ALDH1A1TSHR | |
| SCHEMBL27913441 | 0.82 | ALDH1A1 (0.36) | TP53ALDH1A1TSHR | |
| SCHEMBL27936310 | 0.78 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL27466001 | 0.78 | ALDH1A1 (0.34) | ALDH1A1TSHR | |
| SCHEMBL28009986 | 0.78 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL27458705 | 0.75 | TSHR (0.42) | ALDH1A1TSHR | |
| SCHEMBL29112582 | 0.75 | TSHR (0.31) | ALDH1A1TSHR | |
| SCHEMBL29012646 | 0.73 | — | — | |
| SCHEMBL27436534 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099843-A1 | DOLASTATIN 15 DERIVATIVES | ABBOTT GMBH & CO. KG (DE) | 2010-04-22 | — | — | US | claimed |
| CN-114340374-A | Sowing device and method for treating seeds during planting | 先正达参股股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114269144-A | Precision processing and sowing or planting method and apparatus | 先正达参股股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114269143-A | High precision greenhouse treatment of seeds and seedlings | 先正达参股股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114269145-A | Apparatus and method for converting an existing sowing apparatus | 先正达参股股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114258261-A | Apparatus and method for reducing dust development in precision drilling | 先正达参股股份有限公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-108366559-B | Pest repellant for wasps in family Vespidae | 株式会社KINP | 2021-04-13 | — | — | CN | disclosed |
| CN-112512321-A | Method for controlling soybean rust having resistance to Qo inhibitor | 住友化学株式会社 | 2021-03-16 | — | — | CN | disclosed |
| US-9005920-B2 | Solution for cell-free protein synthesis, kit for cell-free protein synthesis, and method of protein synthesis | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2015-04-14 | — | — | US | disclosed |
| CN-104220575-A | Compositions and methods | INNOSPEC LTD | 2014-12-17 | — | — | CN | disclosed |
| US-7662786-B2 | oligopeptides; anticarcinogenic agent; good water solubility and cost effective; , B, D, E, F, G and K are alpha -amino acid residues, and s and r are each, independently, 0 or 1. L is a monovalent radical, such as,an amino group, an N-substituted amino group, a beta -hydroxylamino group, an alkoxy group | ABBOTT GMBH & CO. KG (DE) | 2010-02-16 | — | — | US | disclosed |
| US-20060270606-A1 | Dolastatin 15 derivatives | ABBOTT GMBH & CO., KG (DE) | 2006-11-30 | — | — | US | disclosed |
| CN-1268636-C | Dolastatin 15 derivatives | ABSF AG (DE) | 2006-08-09 | — | — | CN | disclosed |
| US-7084110-B2 | Anticarcinogenic agents for treating cancer; pentapeptides, hexapeptides, heptapeptides, oligopeptides | ABBOTT GMBH & CO., KG (DE) | 2006-08-01 | — | — | US | disclosed |
| EP-0991658-B1 | DOLASTATIN 15 DERIVATIVES | ABBOTT GMBH & CO KG (DE) | 2005-12-28 | — | — | EP | disclosed |
| US-6458765-B1 | POLYPEPTIDES AS ANTICANCER AGENTS AND AGAINST CELL PROLIFERATION | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-01 | — | — | US | disclosed |
| US-6143721-A | FOR TREATING CANCER IN MAMMALS | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-07 | — | — | US | disclosed |
| CN-1264388-A | Dolastatin 15 derivatives | ABSF AG (DE) | 2000-08-23 | — | — | CN | disclosed |
| EP-0991658-A1 | DOLASTATIN 15 DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999003879-A1 | DOLASTATIN 15 DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099843-A1 | DOLASTATIN 15 DERIVATIVES | DDOST, DBI, DAO | TP53 1827/4885ALDH1A1 1830/4885TSHR 2115/4885 |
| US-20060270606-A1 | Dolastatin 15 derivatives | DDOST, DBI, DAO | TP53 1827/4885ALDH1A1 1830/4885TSHR 2115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.