Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 15/20 | 0.59 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14264699 | 0.93 | CXCR3 (0.63) | CXCR3PDE10AKIF11 | |
| SCHEMBL12829873 | 0.77 | CXCR3 (0.51) | CXCR3PDE10AKIF11 | |
| SCHEMBL12463674 | 0.75 | POLB (0.48) | CXCR3PDE10A | |
| SCHEMBL16152253 | 0.75 | CXCR3 (0.58) | CXCR3PDE10A | |
| SCHEMBL12463979 | 0.74 | CXCR3 (0.60) | CXCR3KIF11 | |
| SCHEMBL12463980 | 0.71 | CXCR3 (0.50) | CXCR3PDE10AKIF11 | |
| SCHEMBL12829861 | 0.70 | CXCR3 (0.88) | CXCR3 | |
| SCHEMBL12464100 | 0.69 | CXCR3 (0.67) | CXCR3 | |
| SCHEMBL12464089 | 0.69 | CXCR3 (0.46) | CXCR3PDE10AKIF11 | |
| SCHEMBL14621132 | 0.68 | CXCR3 (1.00) | CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9173869-B2 | Mediators of hedgehog signaling pathways, compositions and uses related thereto | CURIS, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-20110077256-A1 | MEDIATORS OF HEDGEHOG SIGNALING PATHWAYS, COMPOSITIONS AND USES RELATED THERETO | GUICHERIT OIVIN M | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077256-A1 | MEDIATORS OF HEDGEHOG SIGNALING PATHWAYS, COMPOSITIONS AND USES RELATED THERETO | SHH, SMO, GLI1 | CXCR3 1281/4885PDE10A 1544/4885KIF11 2744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.