Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | AGPAT2 | O15120 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | EIF4E | P06730 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | DUSP1 | P28562 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12756309 | 0.88 | RAB9A (0.43) | TP53MAPTPOLB | |
| SCHEMBL12756317 | 0.87 | DUSP1 (0.41) | TP53RXFP1MAPTPOLBDUSP1 | |
| SCHEMBL12831071 | 0.83 | MAPT (0.43) | TP53RXFP1MAPTPOLBANO1 | |
| SCHEMBL12829835 | 0.80 | MAPT (0.44) | TP53MAPTPOLB | |
| SCHEMBL12830013 | 0.80 | RAB9A (0.41) | TP53MAPTPOLB | |
| SCHEMBL12830474 | 0.80 | TP53 (0.39) | TP53RXFP1MAPTAGPAT2PTGES | |
| SCHEMBL12831073 | 0.80 | ANO1 (0.43) | TP53RXFP1MAPTPOLBANO1 | |
| SCHEMBL12830945 | 0.80 | TP53 (0.45) | TP53RXFP1MAPTPOLBANO1 | |
| SCHEMBL12830947 | 0.80 | ANO1 (0.45) | TP53MAPTPOLBANO1 | |
| SCHEMBL12831077 | 0.79 | KMT2A (0.42) | TP53MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034962-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-03-24 | — | — | WO | disclosed |