SCHEMBL128316

SCHEMBL128316

Cc1csc(C)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2487462 1.00
Iodide SCHEMBL27887241 0.97
Bromide SCHEMBL27485582 0.97
Ammonia Solution, Strong SCHEMBL28692741 0.97
Hydrochloric Acid SCHEMBL11308925 0.97
Benzene SCHEMBL28324907 0.94 NOS1 (0.50)
Hydrochloric Acid SCHEMBL17080156 0.94
Hydrochloric Acid SCHEMBL241181 0.94 SMN1; SMN2 (0.50)
SCHEMBL29227783 0.85 SMN1; SMN2 (0.48)
Formamide SCHEMBL16109412 0.85 SMN1; SMN2 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4391 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250302678-A1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS PROCTER & GAMBLE (US) 2025-10-02 US claimed
US-12350136-B2 Absorbent articles including perfume and cyclodextrins THE PROCTER & GAMBLE COMPANY (US) 2025-07-08 US claimed
CN-120004818-A Preparation method of Piaoning 宜春学院 2025-05-16 CN claimed
US-20240383856-A1 INHIBITORS OF TRANSGLUTAMINASES ZEDIRA GMBH (DE) 2024-11-21 US claimed
CN-221933119-U Leaching device is used in dimethylthiazole production 滕州市悟通香料有限责任公司 2024-11-01 CN claimed
CN-118271972-A Coarse grinding liquid for processing surface of high-purity large-size alumina ceramic substrate and preparation method thereof 宜宾红星电子有限公司 2024-07-02 CN claimed
CN-117683240-A Method for preparing iron-based MOFs by electron beam irradiation, iron-based MOFs and application 上海大学 2024-03-12 CN claimed
EP-4273147-A1 SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2023-11-08 EP claimed
CN-116874478-A Food spice compound and application thereof 宁夏信达昌科技有限公司 2023-10-13 CN claimed
CN-115463692-B N-containing five-membered heterocyclic ligand modified ruthenium-based catalyst for hydrochlorination of acetylene as well as preparation method and application thereof 南开大学 2023-10-10 CN claimed
US-5308853-A Hypotensive agents, antagonists of angiotensin II WARNER-LAMBERT COMPANY (US) 1994-05-03 US claimed
WO-1994007845-A1 N-(HYDROXYETHYL)BUTANEDIAMIDE DERIVATIVES AS RENIN INHIBITORS BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1994-04-14 WO claimed
WO-1994007846-A1 RENIN INHIBITING N-(2-AMINO-2-OXOETHYL)BUTANEDIAMIDE DERIVATIVES BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1994-04-14 WO claimed
EP-0589445-A1 Renin Inhibiting N-(2-Amino-2-oxoethyl)Butanediamide Derivatives BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1994-03-30 EP claimed
EP-0589446-A1 N-(Hydroxyethyl)butanediamide derivatives as renin inhibitors BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1994-03-30 EP claimed
WO-1993013077-A1 ANGIOTENSIN II RECEPTOR ANTAGONISTS WARNER-LAMBERT COMPANY (US) 1993-07-08 WO claimed
EP-0239931-B1 PROCESS AND REAGENT FOR THE DETERMINATION OF SUBSTRATES OR ENZYME ACTIVITIES Roche Diagnostics GmbH (DE) 1992-03-18 EP claimed
US-4558111-A Method for preparing acrylic functional halosilanes and halosiloxanes GENERAL ELECTRIC COMPANY (US) 1985-12-10 US claimed
US-4063894-A CHROMOGEN, HYDROPEROXIDE, THIAZOLE SHIONOGI & CO., LTD. (JA) 1977-12-20 US claimed
US-4025526-A REACTION OF DIETHYLAMINE, ETHYLIDENE-ETHYLAMINE OR DIISOPROPYLAMINE WITH SULFUR NISSAN CHEMICAL INDUSTRIES, LTD. (JA) 1977-05-24 US claimed