Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23105808 | 0.81 | CCNT1 (0.33) | CCNT1CDK9POLBKMT2ALMNA | |
| SCHEMBL20629742 | 0.77 | NPC1 (0.33) | KMT2ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL6864014 | 0.74 | DHFR (0.31) | SMN1; SMN2 | |
| SCHEMBL13729390 | 0.74 | FFAR3 (0.35) | — | |
| SCHEMBL15593749 | 0.73 | NR1H4 (0.36) | NR1H4KMT2ALMNA | |
| SCHEMBL8140531 | 0.72 | HDAC8 (0.31) | HDAC8HDAC6GAA | |
| SCHEMBL4110765 | 0.72 | POLB (0.36) | POLBHTTNAMPTKMT2AHDAC8 | |
| SCHEMBL8275843 | 0.71 | — | — | |
| SCHEMBL883038 | 0.71 | — | — | |
| SCHEMBL15828901 | 0.71 | CA1 (0.31) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4545535-A1 | THIENOPYRIMIDINE DERIVATIVES AS ACC INHIBITORS AND USES THEREOF | Gilead Sciences, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| CN-114206884-B | Thienopyrimidine derivatives as ACC inhibitors and use thereof | 吉利德科学公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-114206884-A | Thienopyrimidine derivatives as ACC inhibitors and uses thereof | 吉利德科学公司 | 2022-03-18 | — | — | CN | disclosed |
| WO-2011038293-A1 | CYCLIC PEPTIDE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2011-03-31 | — | — | WO | disclosed |