SCHEMBL12832008

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12832003	0.86	KDM4E (0.50)	KDM4EALDH1A1GAAHPGDGLA
	SCHEMBL9234953	0.85	DNMT1 (0.46)	KDM4EALDH1A1GAAHPGDGLA
	SCHEMBL1426785	0.82	GRM2 (0.36)	KDM4EALDH1A1GAAHPGDGLA
	SCHEMBL14255060	0.81	KDM4E (0.48)	KDM4EALDH1A1GAAHPGDGLA
	SCHEMBL859189	0.81	KDM4E (0.48)	KDM4EALDH1A1GAAHPGDGLA
	SCHEMBL9117321	0.81	KDM4E (0.48)	KDM4EALDH1A1GAAHPGDGLA
	SCHEMBL8240777	0.80	TLR7 (0.49)	KDM4EALDH1A1GAAHPGDGLA
	SCHEMBL12758859	0.80	GRM2 (0.37)	KDM4EALDH1A1GAAHPGDGLA
	SCHEMBL14255059	0.79	POLB (0.51)	KDM4EALDH1A1GAAHPGDGLA
	SCHEMBL14290281	0.76	KDM4E (0.47)	KDM4EALDH1A1GAAHPGDGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.