SCHEMBL128331

SCHEMBL128331

SCCc1cccc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.54
CYP2C19 P33261 2/20 0.54
CYP2C9 P11712 1/20 0.54
NQO2 P16083 1/20 0.53
CYP2D6 P10635 2/20 0.50
MTNR1A P48039 2/20 0.49
SLC18A2 Q05940 1/20 0.49
TDP1 Q9NUW8 1/20 0.48
ACP3 P15309 1/20 0.47
DAO P14920 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL129738 0.87 CYP1A2 (0.50) CYP1A2CYP2C19CYP2C9NQO2CYP2D6
SCHEMBL3047898 0.85 CYP1A2 (0.62) CYP1A2CYP2C19CYP2C9NQO2CYP2D6
SCHEMBL131057 0.85 CYP1A2 (0.48) CYP1A2CYP2C19CYP2C9NQO2CYP2D6
SCHEMBL134730 0.84 CYP1A2 (0.47) CYP1A2CYP2C19CYP2C9NQO2CYP2D6
SCHEMBL130639 0.84 CYP1A2 (0.47) CYP1A2CYP2C19CYP2C9NQO2CYP2D6
SCHEMBL28899 0.81 CYP1A2 (0.58) CYP1A2CYP2C19CYP2C9CYP2D6TDP1
SCHEMBL5830948 0.81 GPR84 (0.59) CYP1A2CYP2C19CYP2C9NQO2CYP2D6
SCHEMBL9800436 0.81 CYP1A2 (0.58) CYP1A2CYP2C19CYP2C9NQO2CYP2D6
SCHEMBL29114644 0.81 HTR2A (0.41) CYP1A2CYP2C19CYP2C9NQO2MTNR1A
SCHEMBL127565 0.78 CYP1A2 (0.50) CYP1A2CYP2C19CYP2C9NQO2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0659746-B1 Process for the preparation of sulfonylaminocarbonyl-triazolinones BAYER AG (DE) 1998-05-06 EP claimed
US-5550244-A Process for preparing sulphonylaminocarbonyltriazolinones BAYER AKTIENGESELLSCHAFT (DE) 1996-08-27 US claimed
EP-0659746-A1 Process for the preparation of sulfonylaminocarbonyl-triazolinones BAYER AG (DE) 1995-06-28 EP claimed
CN-115504896-B Acrylic formate compound for LED photopolymerization, preparation method and application thereof 湖北固润科技股份有限公司 2024-05-07 CN disclosed
WO-2024078413-A1 ACRYLOYL FORMATE COMPOUND FOR LED PHOTOPOLYMERIZATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF 湖北固润科技股份有限公司 2024-04-18 WO disclosed
CN-117142994-A Amphiphilic polyether alpha-ketone (hetero) arylthioester compound for LED photopolymerization and preparation and application thereof 湖北固润科技股份有限公司 2023-12-01 CN disclosed
CN-117142995-A Pyruvic acid (hetero) arylthioester compound for LED photopolymerization and preparation and application thereof 湖北固润科技股份有限公司 2023-12-01 CN disclosed
EP-3717475-B1 KINASE INHIBITOR COMPOUNDS AND COMPOSITIONS AND METHODS OF USE ICAHN SCHOOL MED MOUNT SINAI (US) 2023-06-07 EP disclosed
CN-115504896-A Acryloyl formate compound for LED photopolymerization, and preparation method and application thereof 湖北固润科技股份有限公司 2022-12-23 CN disclosed
CN-109415513-B Silicon-rich silsesquioxane resins 美国陶氏有机硅公司 2022-02-25 CN disclosed
CN-113997650-A Multilayer structure assembly with force-induced responsiveness 厦门天策材料科技有限公司 2022-02-01 CN disclosed
EP-0826687-A1 Carbapenem derivatives and antimicrobial agents comprising the same SUNTORY LIMITED (JP) 1998-03-04 EP disclosed
EP-0774465-A1 Penem derivatives and antimicrobial agents containing the same SUNTORY LIMITED (JP) 1997-05-21 EP disclosed
EP-0757051-A1 PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME SUNTORY LIMITED (JP) 1997-02-05 EP disclosed
US-5550244-A Process for preparing sulphonylaminocarbonyltriazolinones BAYER AKTIENGESELLSCHAFT (DE) 1996-08-27 US disclosed
EP-0659746-A1 Process for the preparation of sulfonylaminocarbonyl-triazolinones BAYER AG (DE) 1995-06-28 EP disclosed
US-5424325-A Inibitors of thiol protease and may be used as therapeutic agents for treating muscular dystrophy, cataracts, strokes MITSUBISHI KASEI CORPORATION (JP) 1995-06-13 US disclosed
US-4320070-A ION EXCHANGE RESIN CATALYST PPG INDUSTRIES, INC. (US) 1982-03-16 US disclosed
US-4273725-A Process for preparing chlorothiolformates PPG INDUSTRIES, INC. (US) 1981-06-16 US disclosed
US-4268456-A FROM A MERCAPTAN AND PHOSGENE, QUATERNARY AMMONIUM SALT CATALYST PPG INDUSTRIES, INC. (US) 1981-05-19 US disclosed