Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12833143 | 0.94 | — | — | |
| SCHEMBL2130651 | 0.90 | MAPK1 (0.37) | MAPK1 | |
| SCHEMBL2135225 | 0.86 | — | — | |
| SCHEMBL2136636 | 0.85 | — | — | |
| SCHEMBL12832828 | 0.84 | MAPK1 (0.37) | MAPK1 | |
| SCHEMBL2136015 | 0.84 | — | — | |
| SCHEMBL12832829 | 0.83 | ABL1 (0.39) | MAPK1 | |
| SCHEMBL2136693 | 0.82 | — | — | |
| SCHEMBL12833147 | 0.81 | FGFR1 (0.43) | — | |
| SCHEMBL12832827 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011024004-A1 | HETEROCYCLIC UREA DERIVATIVES USEFUL FOR TREATMENT OF BACTERIAL INFECTION | ASTRAZENECA AB (SE) | 2011-03-03 | — | — | WO | disclosed |
| WO-2009106885-A1 | HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF-211 | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | WO | disclosed |