Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | POLA1 | P09884 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 6/20 | 0.52 |
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 4/20 | 0.48 |
| ▸ | CES1 | P23141 | 4/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2600386 | 1.00 | TRPA1 (0.61) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL6060342 | 0.98 | POLB (0.61) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL2081591 | 0.93 | TRPA1 (0.52) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL2081595 | 0.93 | TRPA1 (0.52) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL30705405 | 0.88 | POLB (0.70) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL10808215 | 0.88 | POLB (0.70) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL30705404 | 0.88 | POLB (0.70) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL10808210 | 0.88 | POLB (0.70) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL12257167 | 0.83 | IAPP (0.41) | TRPA1POLBPOLA1PPARGPPARA | |
| SCHEMBL14401623 | 0.83 | IAPP (0.41) | TRPA1POLBPOLA1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289974-A2 | Polyhedral oligomeric silsesquioxane image conditioning coating | Xerox Corporation (US) | 2011-03-02 | — | — | EP | disclosed |