Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1448571 | 0.87 | GPR119 (1.00) | GPR119 | |
| SCHEMBL1448572 | 0.87 | GPR119 (1.00) | GPR119 | |
| SCHEMBL1448634 | 0.85 | GPR119 (1.00) | GPR119 | |
| SCHEMBL1448631 | 0.85 | GPR119 (1.00) | GPR119 | |
| SCHEMBL1448485 | 0.85 | GPR119 (1.00) | GPR119 | |
| SCHEMBL1448487 | 0.85 | GPR119 (1.00) | GPR119 | |
| SCHEMBL1447995 | 0.82 | GPR119 (1.00) | GPR119 | |
| SCHEMBL1447992 | 0.82 | GPR119 (1.00) | GPR119 | |
| SCHEMBL1448023 | 0.82 | GPR119 (1.00) | GPR119 | |
| SCHEMBL1447888 | 0.82 | GPR119 (1.00) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011030139-A1 | 4- (PYRIMIDIN-2-YL) -PIPERAZINE AND 4- (PYRIMIDIN-2-YL) -PIPERIDINE DERIVATIVES AS GPR119 MODULATORS | ASTRAZENECA AB (SE) | 2011-03-17 | — | — | WO | disclosed |