SCHEMBL12834337

SCHEMBL12834337

CCCC1CCC(c2ccc(CCc3ccc(C(C)O)c(F)c3F)c(C(F)(F)F)c2F)CC1

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.31
OPRL1 P41146 1/20 0.31
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
MEN1 O00255 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13026099 0.83 S1PR1 (0.30) CYP2C9ALDH1A1MAPT
SCHEMBL11938475 0.82 F2RL1 (0.30)
SCHEMBL7670108 0.81 CYP2C9 (0.36) CYP2C9OPRL1ALDH1A1LMNAMAPT
SCHEMBL7670105 0.81 CYP2C9 (0.36) CYP2C9OPRL1ALDH1A1LMNAMAPT
SCHEMBL7670118 0.81 CYP2C9 (0.36) CYP2C9OPRL1ALDH1A1LMNAMAPT
SCHEMBL12834339 0.80
SCHEMBL12833694 0.80 CYP2C9 (0.33) CYP2C9OPRL1ALDH1A1LMNAMAPT
SCHEMBL12907514 0.79
SCHEMBL12834319 0.78 OPRL1 (0.32) CYP2C9OPRL1ALDH1A1LMNAMAPT
SCHEMBL10302890 0.78 LNPEP (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1731493-B1 BENZENE DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY CHISSO CORP (JP) 2011-03-23 EP disclosed
US-7838087-B2 Benzene derivative, liquid crystal composition and liquid crystal display device CHISSO CORPORATION (JP) 2010-11-23 US disclosed