Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.53 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12835026 | 0.95 | TMPRSS4 (0.58) | TMPRSS4KDRGRM4PDK1MAPT | |
| SCHEMBL12172804 | 0.88 | TAS2R14 (0.55) | TMPRSS4MAPTLMNAMEN1KMT2A | |
| SCHEMBL330566 | 0.86 | TMPRSS4 (0.77) | TMPRSS4KDRGRM4PDK1MAPT | |
| SCHEMBL12835394 | 0.86 | TMPRSS4 (0.59) | TMPRSS4KDRGRM4PDK1MAPT | |
| SCHEMBL12835398 | 0.86 | TMPRSS4 (0.59) | TMPRSS4KDRGRM4PDK1MAPT | |
| SCHEMBL12835410 | 0.85 | GRM4 (0.64) | TMPRSS4KDRGRM4PDK1MAPT | |
| SCHEMBL12172808 | 0.82 | TAS2R14 (0.55) | TMPRSS4MAPTLMNAMEN1KMT2A | |
| SCHEMBL12835395 | 0.81 | TMPRSS4 (0.59) | TMPRSS4KDRGRM4PDK1MAPT | |
| SCHEMBL12835396 | 0.81 | TMPRSS4 (0.59) | TMPRSS4KDRGRM4PDK1MAPT | |
| SCHEMBL18804918 | 0.79 | GRM4 (0.63) | TMPRSS4KDRGRM4PDK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011026107-A1 | PHTHALANILATE COMPOUNDS AND METHODS OF USE | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2011-03-03 | — | — | WO | disclosed |