TAS2R14 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL184034	0.51	13/20
SCHEMBL1026299	0.64	12/20
SCHEMBL183826	0.59	11/20
SCHEMBL184516	0.52	11/20
SCHEMBL665429	0.60	10/20
SCHEMBL428462	0.49	9/20
SCHEMBL984791	0.71	8/20
SCHEMBL184479	0.58	8/20
Halazone (SCHEMBL29353)	0.54	8/20
SCHEMBL174173	0.50	8/20
SCHEMBL184901	0.62	7/20
SCHEMBL184613	0.52	7/20
SCHEMBL184687	0.47	7/20
SCHEMBL185080	0.46	7/20
SCHEMBL456368	0.45	7/20
SCHEMBL184448	0.42	7/20
SCHEMBL185096	0.41	7/20
SCHEMBL849338	0.33	7/20
SCHEMBL879794	0.33	7/20
SCHEMBL384593	0.62	6/20

Clinical trials — most relevant to TAS2R14 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Clinical Trial of Efficacy and Safety of Raphamin in the Treatment of Coronavirus Disease 2019 in Outpatients	PHASE3	COMPLETED
Impact of Flavors on Nicotine Perception and Self-Administration Via E-cigarettes	PHASE2	COMPLETED
Role of the Gut Sweet Taste Receptor in the Secretion of Satiation Peptides	PHASE1	COMPLETED
Role of the Gut Sweet Taste Receptor in the Secretion of Glucagon-like Peptide-1 and Peptide YY	PHASE1	COMPLETED
Sweet Taste Receptors and the Secretion of Glucagon-like Peptide-1 and Peptide YY	PHASE1	COMPLETED
TAS1R1, TAS1R3, TLR2, TLR4, CA6 Gene Polymorphism on Dental Caries	nan	COMPLETED
Vegetables Intake and Polymorphism TAS2R38 Gene by Healthy Adults	nan	COMPLETED
Allele-specific Expression of a Bitter Taste Receptor	nan	COMPLETED
Flavour Programming: Fruit and Vegetable Palatability	nan	COMPLETED
NUTRACORE, Glycaemic Index and Appetite	nan	COMPLETED
Bitter Taste Receptors in Oropharynx Cancer	nan	UNKNOWN
The Effect of Lactisole on the Responses to Glucose Solution	nan	UNKNOWN
Fructose and Glucose and TAS1R2 in Type 1 Diabetes	nan	COMPLETED
Sucralose and Lactisole Additions to OGTT in Humans	nan	COMPLETED
Study of Taste Deficits	nan	COMPLETED
Sensory Study: Taste and Tongue Biology	nan	COMPLETED
Taste Perception and Chronic Disease Risk	nan	COMPLETED
Taste Preferences for Nutritive and Non Nutritive Sweeteners Among Children and Adults	nan	COMPLETED
Gustin Gene Polymorphism and 6-n-propylthiouracil (PROP) Taste	nan	COMPLETED
Ibuprofen Inhibits Human Sweet Taste	nan	COMPLETED
Genetic Variability in Taste Perception	nan	COMPLETED
A Study of the Function of Hormones Present In Taste Buds	nan	COMPLETED
Astringency and Oral Health	nan	COMPLETED
Factors Affecting Salt Intake in Young Adults	nan	UNKNOWN
CD36 and Human Fat Taste Perception	nan	COMPLETED
Sensitive Periods in Early Flavor Learning	nan	COMPLETED
The Effect of Artificial Sweeteners on Blood Glucose Response	nan	WITHDRAWN
Adaptation Strategies for Coping With the Impact of Sensory Alterations on Eating Behavior in Children With Cancer: A Qualitative Study From the Perspective of Children and Parents	nan	NOT_YET_RECRUITING
Impacts of Sugar-Sweetened Beverage on Body Weight	nan	COMPLETED
The Obese Taste Bud Study	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a TAS2R14 binder may also engage these)

Protein	Name	Similarity
Q646D9	—	1.000	Q646D9 →
Q646B7	—	1.000	Q646B7 →
Q645Z2	—	1.000	Q645Z2 →
Q645V2	—	1.000	Q645V2 →
Q67ET3	—	0.997	Q67ET3 →
Q7M713	—	0.997	Q7M713 →
Q67ES0	—	0.995	Q67ES0 →
P59528	—	0.994	P59528 →
Q646C4	—	0.994	Q646C4 →
Q7M711	—	0.994	Q7M711 →
Q7M712	—	0.994	Q7M712 →
Q67ET5	—	0.994	Q67ET5 →
Q9JKA3	—	0.994	Q9JKA3 →
P59530	—	0.994	P59530 →
Q7M721	—	0.993	Q7M721 →
Q646B6	—	0.993	Q646B6 →
Q675B9	—	0.993	Q675B9 →
Q645T7	—	0.992	Q645T7 →
Q646D8	—	0.991	Q646D8 →
Q646F7	—	0.991	Q646F7 →
TAS2R7	Taste receptor type 2 member 7	0.991	landscape →
Q645Z5	—	0.991	Q645Z5 →
Q646G0	—	0.990	Q646G0 →
Q645T9	—	0.990	Q645T9 →
Q9JKE9	—	0.990	Q9JKE9 →
Q7M710	—	0.990	Q7M710 →
Q7M725	—	0.990	Q7M725 →
Q67ER8	—	0.990	Q67ER8 →
Q645V0	—	0.990	Q645V0 →
Q7M707	—	0.990	Q7M707 →