Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875368 | 0.85 | GLA (0.63) | KDM4EMEN1CYP3A4KMT2ALMNA | |
| SCHEMBL12835497 | 0.82 | ABCG2 (0.60) | ABCG2KDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL9550449 | 0.81 | GLA (0.56) | KDM4ECYP3A4LMNAGLASTING1 | |
| SCHEMBL31290902 | 0.80 | ABCG2 (0.68) | ABCG2KDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL15899627 | 0.80 | ABCG2 (0.54) | ABCG2KDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL8875864 | 0.79 | ABCG2 (0.63) | ABCG2KDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL31286535 | 0.79 | ABCG2 (0.53) | ABCG2KDM4EMEN1CYP3A4KMT2A | |
| SCHEMBL107952 | 0.77 | KDM4E (0.71) | KDM4ECYP3A4LMNAGLASTING1 | |
| SCHEMBL29975151 | 0.77 | KDM4E (0.71) | KDM4ECYP3A4LMNAGLASTING1 | |
| SCHEMBL15676500 | 0.77 | ABCG2 (0.65) | ABCG2KDM4EMEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023287-A1 | USE OF FAA AND ITS DERIVATIVES IN COSMETICS AND DERMATOLOGY | MERCK PATENT GMBH (DE) | 2011-03-03 | — | — | WO | disclosed |