SCHEMBL29975151

SCHEMBL29975151

O=C(O)Cc1cccc2c(=O)c3ccccc3oc12

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.71
GLA P06280 2/20 0.63
STING1 Q86WV6 1/20 0.63
MAOA P21397 5/20 0.58
CYP19A1 P11511 1/20 0.52
CYP11B1 P15538 1/20 0.52
CYP11B2 P19099 1/20 0.52
PTGS2 P35354 1/20 0.51
ALDH1A1 P00352 2/20 0.50
CYP3A4 P08684 1/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
PGAM1 P18669 1/20 0.50
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
NPC1 O15118 1/20 0.50
LMNA P02545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL107952 1.00 KDM4E (0.71) KDM4EGLASTING1MAOACYP19A1
Trimethylammonium SCHEMBL27716678 0.94 KDM4E (0.68) KDM4EGLASTING1MAOACYP19A1
SCHEMBL11192241 0.89 ALOX5 (0.60) KDM4EGLASTING1MAOATDP1
SCHEMBL27318901 0.85 KDM4E (0.60) KDM4EGLASTING1MAOACYP19A1
SCHEMBL10999959 0.84 KDM4E (0.65) KDM4EGLAMAOACYP19A1CYP11B1
SCHEMBL9376244 0.84 STING1 (0.62) KDM4EGLASTING1MAOAALDH1A1
SCHEMBL7140586 0.83 MAOA (0.57) KDM4EGLASTING1MAOACYP19A1
SCHEMBL20762953 0.83 GLA (0.64) KDM4EGLASTING1MAOAPTGS2
SCHEMBL9376949 0.82 TTR (0.55) KDM4EGLASTING1MAOAALDH1A1
SCHEMBL3273835 0.81 KDM4E (0.77) KDM4EGLASTING1MAOACYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421308-B2 Anti-G-CSF antibodies and uses thereof ME THERAPEUTICS INC. 2025-09-23 US disclosed
WO-2025043029-A1 METHODS AND DEVICES ON SLOPE ADJUSTMENT FOR IBC LIC AND FILTERED IBC AND FILTERED INTRA TMP AND CCCM AND GLM BEIJING DAJIA INTERNET INFORMATION TECHNOLOGY CO., LTD (CN) 2025-02-27 WO disclosed
US-20230159631-A1 ANTI-G-CSF ANTIBODIES AND USES THEREOF ME THERAPEUTICS INC. (CA) 2023-05-25 US disclosed
WO-2022210465-A1 NANOGEL-COATED VACCINE 国立大学法人東京大学 2022-10-06 WO disclosed