Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 6/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 2/20 | 0.46 |
| ▸ | RET | P07949 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12836348 | 0.89 | HRH2 (0.50) | SUV39H2CTSKACACBRETMEN1 | |
| SCHEMBL12836076 | 0.88 | BTK (0.53) | SUV39H2CTSKPIM1PIM3PIM2 | |
| SCHEMBL12835665 | 0.88 | CTSK (0.53) | SUV39H2CTSKPIM1PIM3PIM2 | |
| SCHEMBL12836173 | 0.87 | HRH2 (0.45) | SUV39H2CTSKACACBALDH1A1HPGD | |
| SCHEMBL12836043 | 0.87 | CTSK (0.52) | SUV39H2CTSKPIM1PIM3PIM2 | |
| SCHEMBL31318667 | 0.86 | SUV39H2 (0.51) | SUV39H2CTSKPIM1PIM3PIM2 | |
| SCHEMBL12835985 | 0.85 | SUV39H2 (0.53) | SUV39H2CTSKPIM1PIM3PIM2 | |
| SCHEMBL12836025 | 0.85 | CTSK (0.50) | SUV39H2CTSKPIM1PIM3PIM2 | |
| SCHEMBL12836009 | 0.84 | PIM1 (0.50) | SUV39H2CTSKPIM1PIM3PIM2 | |
| SCHEMBL12835989 | 0.84 | PIM1 (0.58) | SUV39H2CTSKPIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011025799-A1 | CATHEPSIN C INHIBITORS | GLAXO GROUP LIMITED (GB) | 2011-03-03 | — | — | WO | disclosed |