Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | IDH2 | P48735 | 2/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1514544 | 0.99 | FFAR2 (0.44) | FFAR2CHRM4DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL1514406 | 0.99 | FFAR2 (0.44) | FFAR2CHRM4DPP4DPP8DPP9 | |
| SCHEMBL12835674 | 0.90 | SMN1; SMN2 (0.42) | FFAR2CHRM4SMN1; SMN2TSHRKDM1A | |
| Hydrochloric Acid SCHEMBL1514680 | 0.89 | SMN1; SMN2 (0.41) | FFAR2CHRM4SMN1; SMN2TSHRKDM1A | |
| Hydrochloric Acid SCHEMBL1514458 | 0.89 | SMN1; SMN2 (0.41) | FFAR2CHRM4SMN1; SMN2TSHRKDM1A | |
| SCHEMBL22186838 | 0.83 | IDH2 (0.43) | IDH2LIPGLPLCYP3A4MAPT | |
| SCHEMBL22186371 | 0.83 | IDH2 (0.43) | IDH2LIPGLPLCYP3A4MAPT | |
| SCHEMBL13175769 | 0.82 | AR (0.52) | FFAR2CHRM4DPP4DPP8DPP9 | |
| SCHEMBL4635419 | 0.82 | DPP4 (0.49) | FFAR2CHRM4DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL28919352 | 0.82 | IDH2 (0.43) | IDH2LIPGLPLCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011025799-A1 | CATHEPSIN C INHIBITORS | GLAXO GROUP LIMITED (GB) | 2011-03-03 | — | — | WO | disclosed |