Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 6/20 | 0.54 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.48 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 4/20 | 0.46 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12835985 | 0.93 | SUV39H2 (0.53) | SUV39H2CTSKJAK3BTKPIM1 | |
| SCHEMBL12835989 | 0.84 | PIM1 (0.58) | SUV39H2CTSKJAK3BTKPIM1 | |
| SCHEMBL12836149 | 0.84 | SUV39H2 (0.50) | SUV39H2CTSKJAK3BTKPIM1 | |
| SCHEMBL25597599 | 0.84 | SUV39H2 (0.57) | SUV39H2CTSKJAK3BTKRET | |
| SCHEMBL13651242 | 0.84 | SUV39H2 (0.57) | SUV39H2CTSKJAK3BTKKDM4D | |
| SCHEMBL12835967 | 0.83 | SUV39H2 (0.49) | SUV39H2CTSKJAK3BTKPIM1 | |
| SCHEMBL24508115 | 0.82 | SUV39H2 (0.56) | SUV39H2CTSKJAK3BTKKDM4D | |
| SCHEMBL29663913 | 0.82 | SUV39H2 (0.56) | SUV39H2CTSKJAK3BTKKDM4D | |
| SCHEMBL12835978 | 0.82 | CTSK (0.53) | SUV39H2CTSKJAK3BTKPIM1 | |
| SCHEMBL5220499 | 0.82 | KDM4D (0.53) | SUV39H2CTSKRETKDM4DKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011025799-A1 | CATHEPSIN C INHIBITORS | GLAXO GROUP LIMITED (GB) | 2011-03-03 | — | — | WO | disclosed |