Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28087512 | 0.88 | POLB (0.36) | OPRM1POLBSLC6A4KMT2AMEN1 | |
| SCHEMBL1684321 | 0.85 | OPRM1 (0.46) | OPRM1SMYD3POLBSLC6A4SLC6A2 | |
| SCHEMBL29210900 | 0.84 | MEN1 (0.40) | OPRM1POLBKMT2AMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL1282061 | 0.84 | OPRM1 (0.44) | OPRM1SMYD3POLBSLC6A4SLC6A2 | |
| SCHEMBL963382 | 0.82 | OPRM1 (0.51) | OPRM1SMYD3POLBSLC6A4SLC6A2 | |
| SCHEMBL13268736 | 0.81 | OPRM1 (0.50) | OPRM1SMYD3POLBSLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL1282849 | 0.81 | OPRM1 (0.50) | OPRM1SMYD3POLBSLC6A4SLC6A2 | |
| SCHEMBL18367201 | 0.80 | TSHR (0.39) | POLBKMT2AMEN1NPC1RAB9A | |
| SCHEMBL390562 | 0.79 | OPRM1 (0.49) | OPRM1SMYD3POLBSLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL20137680 | 0.79 | OPRM1 (0.49) | OPRM1SMYD3POLBSLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023224853-A1 | AT2R ANTAGONISTS AND USES THEREOF | ELI LILLY AND COMPANY (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2011025690-A1 | NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2011-03-03 | — | — | WO | disclosed |