Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH5 | P11766 | 15/20 | 0.77 |
| ▸ | TACR3 | P29371 | 6/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1516289 | 0.91 | ADH5 (0.74) | ADH5TACR3GAAALDH1A1CYP3A4 | |
| SCHEMBL12836445 | 0.90 | ADH5 (0.79) | ADH5TACR3 | |
| SCHEMBL1516352 | 0.87 | ADH5 (1.00) | ADH5TACR3 | |
| SCHEMBL877202 | 0.87 | ADH5 (1.00) | ADH5TACR3 | |
| SCHEMBL876256 | 0.87 | ADH5 (0.74) | ADH5TACR3GAAALDH1A1CYP3A4 | |
| SCHEMBL877943 | 0.87 | ADH5 (1.00) | ADH5TACR3 | |
| SCHEMBL877383 | 0.84 | ADH5 (0.94) | ADH5TACR3 | |
| SCHEMBL1515742 | 0.81 | ADH5 (0.77) | ADH5TACR3 | |
| SCHEMBL873520 | 0.81 | ADH5 (0.77) | ADH5TACR3 | |
| SCHEMBL872907 | 0.81 | ADH5 (0.77) | ADH5TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011038204-A1 | NOVEL DIHYDROPYRIMIDIN-2(1H)-ONE COMPOUNDS AS S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS | N30 PHARMACEUTICALS, LLC (US) | 2011-03-31 | — | — | WO | disclosed |