ADH5

Alcohol dehydrogenase class-3 · P11766 · ADH5 on Sugi Atlas →

7,182 patent compounds predicted against ADH5, 3,255 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL369132 SCHEMBL369132 0.79 20/20
SCHEMBL872907 SCHEMBL872907 0.77 20/20
SCHEMBL873520 SCHEMBL873520 0.77 20/20
SCHEMBL1515742 SCHEMBL1515742 0.77 20/20
SCHEMBL873053 SCHEMBL873053 0.76 20/20
SCHEMBL358225 SCHEMBL358225 0.68 20/20
SCHEMBL876525 SCHEMBL876525 0.63 20/20
SCHEMBL876974 SCHEMBL876974 0.63 20/20
SCHEMBL1516242 SCHEMBL1516242 0.63 20/20
SCHEMBL1515707 SCHEMBL1515707 0.62 20/20
SCHEMBL368440 SCHEMBL368440 0.61 20/20
SCHEMBL876440 SCHEMBL876440 1.00 19/20
SCHEMBL876441 SCHEMBL876441 1.00 19/20
SCHEMBL877325 SCHEMBL877325 1.00 19/20
SCHEMBL877326 SCHEMBL877326 1.00 19/20
SCHEMBL1516247 SCHEMBL1516247 1.00 19/20
SCHEMBL1516310 SCHEMBL1516310 1.00 19/20
SCHEMBL877132 SCHEMBL877132 0.86 19/20
SCHEMBL877696 SCHEMBL877696 0.83 19/20
SCHEMBL876894 SCHEMBL876894 0.81 19/20

Clinical trials — most relevant to ADH5 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The Late Effects of Ethanol Intake on the Glucose Response to Subcutaneous Glucagon in Type 1 Diabetes PHASE4COMPLETED
Pharmacogenetic Study of Ondansetron in Alcohol Use Disorder PHASE2COMPLETED
Predicting Alcoholics' Treatment Responses to a Selective Serotonin Re-uptake Inhibitor (SSRI) PHASE2COMPLETED
Modafinil vs Placebo for the Treatment of Methamphetamine Dependence PHASE2COMPLETED
Non-oxidative Metabolite Profiles After Increasing Doses of Ethanol PHASE1COMPLETED
Nicotinic Receptor Genetic Variation and Alcohol Reward PHASE1RECRUITING
Alcohol Inhibits Drug Metabolism by Carboxylesterases PHASE1COMPLETED
Investigating the Mu:Kappa Opioid Receptor Imbalance in Alcohol Use Disorder EARLY_PHASE1RECRUITING
ALDH2 Genetic Testing in East Asian Community nanNOT_YET_RECRUITING
Bipolar Disorder With Alcoholism in Han Chinese nanUNKNOWN
Environmental and Biological Monitoring Pilot Study for Polycyclic Aromatic Hydrocarbons in Linxian, China nanCOMPLETED
Alcohol Metabolism and Disease Risk in Asians nanCOMPLETED
Hepatic Lipid Metabolism-Alcohol Use Disorder nanRECRUITING
Pharmacogenetics of Alcohol: Treatment Implications nanCOMPLETED
Validation in Humans of Genes Involved in Alcohol Drinking, Stress-Induced Alcohol Drinking and Relapse nanCOMPLETED
Endophenotyping With Functional Magnetic Resonance Imaging (fMRI) nanCOMPLETED
Acamprosate: Genes Associated With Response nanCOMPLETED
Dose-response Effect of Alcohol Ingestion on Steroid Profile nanCOMPLETED
Biomarkers for the Detection of Heavy Alcohol Use in Patients With and Without Liver Disease nanACTIVE_NOT_RECRUITING
ALDH2 Single Nucleotide Polymorphisms and Prognosis of Esophageal Cancer Patients nanRECRUITING
Learning and Relapse Risk in Alcohol Dependence nanCOMPLETED
Understanding Genetic Risk for Alcohol Use Disorder nanCOMPLETED
Dissecting the Genetics of Fetal Alcohol Spectrum Disorders nanCOMPLETED
Clinical-Genetic Variation in GABA/Alcohol Sensitivity nanCOMPLETED
Alcohol Consumption and Circulating Metabolites nanCOMPLETED
Genetic and Environmental Risk Factors Related to Esophageal Cancer nanACTIVE_NOT_RECRUITING
The Genetic Basis for Vulnerability to Substance Abuse nanCOMPLETED
GABA Mechanisms Underlying the Vulnerability to Alcohol Dependence nanCOMPLETED
Pharmacogenetic Determinants Of Treatment Response In Children nanRECRUITING
Biobehavioral Pathways Underlying Alcohol Use and Health nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a ADH5 binder may also engage these)

ProteinNameSimilarity
P19854 1.000 P19854 →
Q3ZC42 1.000 Q3ZC42 →
O19053 1.000 O19053 →
P28474 1.000 P28474 →
P79896 1.000 P79896 →
P12711 1.000 P12711 →
P80467 1.000 P80467 →
P00328 1.000 P00328 →
ADH1C Alcohol dehydrogenase 1C 1.000 landscape →
P93629 1.000 P93629 →
P80338 1.000 P80338 →
Q96533 1.000 Q96533 →
Q64415 1.000 Q64415 →
P81601 1.000 P81601 →
P86885 1.000 P86885 →
P81600 1.000 P81600 →
P19631 1.000 P19631 →
P81431 1.000 P81431 →
P23991 1.000 P23991 →
Q5R1W2 1.000 Q5R1W2 →
P49645 1.000 P49645 →
ADH1B All-trans-retinol dehydrogenase [NAD(+)] ADH1B 1.000 landscape →
P14139 1.000 P14139 →
Q0DWH1 1.000 Q0DWH1 →
P80222 1.000 P80222 →
P80360 1.000 P80360 →
ADH1A Alcohol dehydrogenase 1A 1.000 landscape →
P00329 1.000 P00329 →
P00327 1.000 P00327 →
P80512 1.000 P80512 →