Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 5/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12836412 | 0.88 | ADRB2 (0.49) | ADRB2STAT3ELANETOP2ATOP2B | |
| SCHEMBL12836413 | 0.87 | ADRB2 (0.48) | ADRB2STAT3ELANETOP2ATOP2B | |
| SCHEMBL7843532 | 0.84 | ADRB2 (0.54) | ADRB2STAT3ELANETOP2ATOP2B | |
| SCHEMBL115123 | 0.83 | ADRB2 (0.54) | ADRB2STAT3TOP2ATOP2BKMT2A | |
| SCHEMBL12835804 | 0.82 | ADRB2 (0.44) | ADRB2STAT3TOP2ATOP2BKMT2A | |
| SCHEMBL8692136 | 0.82 | ADRB2 (0.47) | ADRB2STAT3ELANETOP2ATOP2B | |
| SCHEMBL115991 | 0.82 | ADRB2 (0.62) | ADRB2STAT3TOP2ATOP2BKMT2A | |
| SCHEMBL12836211 | 0.81 | ADRB2 (0.48) | ADRB2STAT3ELANETOP2ATOP2B | |
| SCHEMBL2844967 | 0.78 | ADRB2 (0.68) | ADRB2STAT3TOP2ATOP2BKMT2A | |
| SCHEMBL29492858 | 0.78 | ADRB2 (0.68) | ADRB2STAT3TOP2ATOP2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011031745-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2011-03-17 | — | — | WO | disclosed |