Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18667233 | 0.89 | TNK2 (0.35) | HRH4HRH3LMNATAAR1TNK2 | |
| SCHEMBL18666910 | 0.89 | TNK2 (0.35) | HRH4HRH3LMNATAAR1TNK2 | |
| SCHEMBL12294892 | 0.89 | TNK2 (0.35) | HRH4HRH3LMNATAAR1TNK2 | |
| SCHEMBL19343805 | 0.88 | HRH4 (0.31) | HRH4HRH3LMNATNK2 | |
| SCHEMBL19343808 | 0.88 | HRH4 (0.31) | HRH4HRH3LMNATNK2 | |
| SCHEMBL12835934 | 0.81 | HRH4 (0.33) | HRH4HRH3LMNA | |
| SCHEMBL12243125 | 0.81 | HRH4 (0.33) | HRH4HRH3LMNA | |
| SCHEMBL22569956 | 0.78 | HRH4 (0.32) | HRH4HRH3LMNATNK2 | |
| SCHEMBL14052168 | 0.77 | TNK2 (0.35) | HRH4HRH3LMNATAAR1TNK2 | |
| SCHEMBL18666854 | 0.77 | TNK2 (0.35) | HRH4HRH3LMNATAAR1TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011035250-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 1'-SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS | GILEAD SCIENCES, INC. (US) | 2011-03-24 | — | — | WO | disclosed |