Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GJB2 | P29033 | 5/20 | 0.45 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.40 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FGF1 | P05230 | 3/20 | 0.35 |
| ▸ | FGF2 | P09038 | 3/20 | 0.35 |
| ▸ | VEGFA | P15692 | 3/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.34 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.34 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13620137 | 0.95 | GJB2 (0.46) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL12837359 | 0.91 | GJB2 (0.42) | GJB2MAPK1FGF1FGF2VEGFA | |
| SCHEMBL16255822 | 0.91 | GJB2 (0.42) | GJB2MAPK1FGF1FGF2VEGFA | |
| SCHEMBL15481944 | 0.88 | GJB2 (0.42) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL18311512 | 0.88 | GJB2 (0.49) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL16374731 | 0.85 | GJB2 (0.45) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL14670875 | 0.85 | GJB2 (0.45) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL18333049 | 0.85 | GJB2 (0.45) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL18332876 | 0.85 | GJB2 (0.45) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL15255429 | 0.85 | GJB2 (0.54) | GJB2SSTR1SSTR2SSTR4SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120263649-A1 | DETECTION OF MYCOBACTERIA | ISIS INNOVATION LIMITED (GB) | 2012-10-18 | — | — | US | disclosed |
| WO-2011030160-A1 | DETECTION OF MYCOBACTERIA | ISIS INNOVATION LIMITED (GB) | 2011-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120263649-A1 | DETECTION OF MYCOBACTERIA | LY96, MICA, CD74 | GJB2 3072/4885SSTR1 3205/4885SSTR2 3750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.