SCHEMBL1283863

SCHEMBL1283863

C=CC(=O)OCC(CC)CCCC.C=CC(=O)OCCCC.C=COC(=O)CC=CC(=O)O

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.60
HPGD P15428 1/20 0.46
HCAR2 Q8TDS4 4/20 0.44
CYP3A4 P08684 4/20 0.41
TDP1 Q9NUW8 2/20 0.41
ATM Q13315 2/20 0.41
RECQL P46063 1/20 0.37
ALDH1A1 P00352 5/20 0.36
CA2 P00918 1/20 0.36
LMNA P02545 3/20 0.33
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
MMP14 P50281 1/20 0.33
MAPK1 P28482 2/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL516622 0.96 TSHR (0.66) TSHRHPGDHCAR2CYP3A4TDP1
SCHEMBL5464973 0.88 TSHR (0.59) TSHRHPGDHCAR2CYP3A4ATM
Acrylic Acid SCHEMBL3844152 0.84 TSHR (0.81) TSHRHPGDHCAR2CYP3A4TDP1
Acrylic Acid SCHEMBL7263337 0.84 TSHR (0.81) TSHRHPGDHCAR2CYP3A4TDP1
SCHEMBL497406 0.84 TSHR (0.48) TSHRHPGDCYP3A4TDP1ATM
SCHEMBL4125846 0.84 TSHR (0.58) TSHRHPGDHCAR2CYP3A4TDP1
Acrylic Acid SCHEMBL16151343 0.84 TSHR (0.67) TSHRHPGDHCAR2CYP3A4TDP1
SCHEMBL338002 0.83 TSHR (0.88) TSHRHPGDHCAR2CYP3A4TDP1
SCHEMBL6133965 0.82 TSHR (0.72) TSHRHPGDHCAR2CYP3A4TDP1
Acrylic Acid Methyl Ester SCHEMBL5718144 0.80 TSHR (0.72) TSHRHPGDHCAR2CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120088053-A1 Release Sheet and Pressure-Sensitive Adhesive Article LINTEC CORPORATION 2012-04-12 US disclosed
US-20100215881-A1 DOUBLE-FACED PRESSURE-SENSITIVE ADHESIVE SHEET USED FOR ELECTRONIC COMPONENTS AND PRODUCING METHOD THEREOF LINTEC CORPORATION (JP) 2010-08-26 US disclosed
US-20100021669-A1 RELEASE SHEET AND PRESSURE-SENSITIVE ADHESIVE ARTICLE LINTEC CORPORATION (JP) 2010-01-28 US disclosed
US-20050226919-A1 Device for transdermal administration for the treatment of urinary tract disorders UCB PHARMA GMBH (DE) 2005-10-13 US disclosed
EP-1293198-B1 Device for transdermal administration for the treatment of urinary tract disorders SANOL ARZNEI SCHWARZ GMBH (DE) 2005-02-09 EP disclosed
WO-2003024432-A2 DEVICE FOR TRANSDERMAL ADMINISTRATION FOR THE TREATMENT OF URINARY TRACT DISORDERS SCHWARZ PHARMA AG (DE) 2003-03-27 WO disclosed
EP-1293198-A1 Device for transdermal administration for the treatment of urinary tract disorders SCHWARZ PHARMA AG (DE) 2003-03-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050226919-A1 Device for transdermal administration for the treatment of urinary tract disorders AR, CYP17A1, TACR1 TSHR 465/4885HPGD 287/4885HCAR2 504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.