SCHEMBL516622

SCHEMBL516622

C=CC(=O)OCC(CC)CCCC.C=COC(=O)CC=CC(=O)O

nearest known ligand 0.66

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.66
CYP3A4 P08684 4/20 0.45
TDP1 Q9NUW8 2/20 0.45
ATM Q13315 1/20 0.45
RECQL P46063 1/20 0.39
ALDH1A1 P00352 5/20 0.38
CA2 P00918 1/20 0.38
HPGD P15428 1/20 0.38
HCAR2 Q8TDS4 3/20 0.36
LMNA P02545 3/20 0.36
MAPK1 P28482 3/20 0.35
HSD17B10 Q99714 1/20 0.35
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
MMP14 P50281 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1283863 0.96 TSHR (0.60) TSHRCYP3A4TDP1ATMRECQL
SCHEMBL497406 0.86 TSHR (0.48) TSHRCYP3A4TDP1ATMRECQL
SCHEMBL6133352 0.83 TSHR (0.53) TSHRCYP3A4TDP1ATMRECQL
Acrylic Acid SCHEMBL2282780 0.83 TSHR (0.91) TSHRCYP3A4TDP1ATMRECQL
SCHEMBL2462155 0.82 TSHR (0.63) TSHRCYP3A4TDP1ATMRECQL
Acrylic Acid SCHEMBL516623 0.82 TSHR (0.74) TSHRCYP3A4TDP1ATMRECQL
SCHEMBL5464973 0.82 TSHR (0.59) TSHRCYP3A4ATMALDH1A1HPGD
SCHEMBL16765797 0.81 TSHR (1.00) TSHRCYP3A4TDP1ATMRECQL
SCHEMBL20609794 0.81 TSHR (1.00) TSHRCYP3A4TDP1ATMRECQL
SCHEMBL14869 0.81 TSHR (1.00) TSHRCYP3A4TDP1ATMRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113853414-B Medical adhesive material 米琪邦株式会社 2023-12-08 CN disclosed
CN-113853414-A Medical adhesive sheet 米琪邦株式会社 2021-12-28 CN disclosed
CN-107001866-B Adhesive material 日绊株式会社 2021-05-04 CN disclosed
EP-3760173-A1 ADHESIVE BANDAGE AND POLYURETHANE NONWOVEN FABRIC FOR ADHESIVE BANDAGE Nichiban Co., Ltd. (JP) 2021-01-06 EP disclosed
CN-111588546-A Medical adhesive material using stretchable pad 日绊株式会社 2020-08-28 CN disclosed
EP-2377498-B1 PRESSURE-SENSITIVE ADHESIVE TAPE PACKAGE HISAMITSU PHARMACEUTICAL CO (JP) 2020-05-27 EP disclosed
CN-105916686-B Coating film 三菱化学株式会社 2020-04-24 CN disclosed
US-20190175415-A1 SKIN CLOSURE TAPE OR REINFORCING TAPE USED AFTER SKIN SUTURE NICHIBAN CO., LTD. (JP) 2019-06-13 US disclosed
EP-3326593-A1 SKIN-SUTURING TAPE OR REINFORCING TAPE USED AFTER SUTURING SKIN Nichiban Co. Ltd. (JP) 2018-05-30 EP disclosed
EP-2191810-B1 COSMETIC AUXILIARY PATCH MATERIAL AND METHOD OF COSMETIZING THEREWITH NICHIBAN KK (JP) 2018-01-03 EP disclosed
US-20100282269-A1 Makeup-Assisting Patch and Makeup Method Using the Patch NICHIBAN CO., LTD. (JP) 2010-11-11 US disclosed
US-20100217171-A1 Patch Material NICHIBAN CO., LTD. (JP) 2010-08-26 US disclosed
EP-2193769-A1 PATCH MATERIAL Nichiban Co. Ltd. (JP) 2010-06-09 EP disclosed
EP-2191810-A1 COSMETIC AUXILIARY PATCH MATERIAL AND METHOD OF COSMETIZING THEREWITH Nichiban Co. Ltd. (JP) 2010-06-02 EP disclosed
US-20090137691-A1 Thermally Foamable Microsphere, Production Process Thereof, and Composition KUREHA CORPORATION 2009-05-28 US disclosed
US-20090068252-A1 Transdermal Absorption Preparation HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2009-03-12 US disclosed
EP-1857519-A1 THERMALLY FOAMABLE MICROSPHERE, PROCESS FOR PRODUCING THE SAME, AND COMPOSITION Kureha Corporation (JP) 2007-11-21 EP disclosed
US-6297421-B1 STRETCHABLE, MOISTURE PERMEABLE, NON-IRRITATING TO SKIN NICHIBAN CO., LTD. (JP) 2001-10-02 US disclosed
EP-1060719-A1 MEDICAL PRESSURE-SENSITIVE ADHESIVE TAPE Nichiban Company Limited (JP) 2000-12-20 EP disclosed
US-4492724-A ELASTOMERIC POLYMER; NONTACKY ACRYLIC ACID POLYMER SYSTEM; NONIONIC SURFACTANT AVERY INTERNATIONAL CORP. (US) 1985-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090068252-A1 Transdermal Absorption Preparation ABCB1, EPCAM, ADRB1 TSHR 2777/4885CYP3A4 85/4885TDP1 1645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.