Dyrene

Dyrene

SCHEMBL1284023

Clc1nc(Cl)nc(Nc2ccccc2Cl)n1.S

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.96
▸ NFKB1 P19838 2/20 0.57
▸ MAPT P10636 5/20 0.54
▸ KMT2A Q03164 5/20 0.54
▸ KDM4E B2RXH2 2/20 0.54
▸ ALDH1A1 P00352 2/20 0.54
▸ SMN1; SMN2 Q16637 2/20 0.54
▸ MEN1 O00255 1/20 0.52
▸ MAPK1 P28482 1/20 0.52
▸ IGF1R P08069 1/20 0.50
▸ NPSR1 Q6W5P4 2/20 0.48
▸ NPC1 O15118 2/20 0.47
▸ RAB9A P51151 2/20 0.47
▸ RAD52 P43351 1/20 0.46
▸ HDAC3 O15379 1/20 0.45
▸ HDAC1 Q13547 1/20 0.45
▸ HDAC2 Q92769 1/20 0.45
▸ HDAC6 Q9UBN7 1/20 0.45
▸ LMNA P02545 1/20 0.44
▸ ADRA2A P08913 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dyrene SCHEMBL11787535 1.00 TSHR (0.96) TSHRNFKB1MAPTKMT2AKDM4E
Dyrene SCHEMBL6281234 1.00 TSHR (0.96) TSHRNFKB1MAPTKMT2AKDM4E
Dyrene SCHEMBL133054 0.98 TSHR (1.00) TSHRNFKB1MAPTKMT2AKDM4E
Dyrene SCHEMBL29364667 0.98 TSHR (1.00) TSHRNFKB1MAPTKMT2AKDM4E
Dyrene SCHEMBL13280 0.98 TSHR (1.00) TSHRNFKB1MAPTKMT2AKDM4E
Dyrene SCHEMBL6750152 0.98 TSHR (1.00) TSHRNFKB1MAPTKMT2AKDM4E
Dyrene SCHEMBL8166670 0.98 TSHR (1.00) TSHRNFKB1MAPTKMT2AKDM4E
Dyrene SCHEMBL1903290 0.98 TSHR (1.00) TSHRNFKB1MAPTKMT2AKDM4E
Dyrene SCHEMBL10918562 0.96 TSHR (0.96) TSHRNFKB1MAPTKMT2AKDM4E
Dyrene SCHEMBL5745643 0.96 TSHR (0.96) TSHRNFKB1MAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059553-A Corrosion and scale inhibition sulfur removal agent and preparation method thereof 成都华阳兴华化工有限公司 2026-05-19 — — CN claimed
US-20250290003-A1 Cluster-Structured, Sulfur Scavenging Composition and Processes for Scavenging Sulfhydryl Moieties in Hydrocarbon Streams THOMPSON JASON MARTIN (US) 2025-09-18 — — US claimed
CN-119614174-A Low-corrosiveness sulfur dissolving agent and preparation method thereof 陕西延长石油(集团)有限责任公司研究院 2025-03-14 — — CN claimed
CN-118813218-A Compound chelating agent, preparation method and application method 中国石油天然气集团有限公司 2024-10-22 — — CN claimed
CN-117343775-A Method for improving compatibility of triazine sulfur-containing compound and hydraulic transmission oil 中国石油天然气股份有限公司 2024-01-05 — — CN claimed
CN-111944560-A Desulfurizing agent for oil and gas fields and preparation method thereof 西安奥德石油工程技术有限责任公司 2020-11-17 — — CN claimed
US-20180105729-A1 WINTERIZING COMPOSITIONS FOR SULFUR SCAVENGERS AND METHODS FOR MAKING AND USING SAME THE LUBRIZOL CORPORATION 2018-04-19 — — US claimed
EP-3268444-A1 WINTERIZING COMPOSITIONS FOR SULFUR SCAVENGERS AND METHODS FOR MAKING AND USING SAME Lubrizol Oilfield Solutions, Inc. (US) 2018-01-17 — — EP claimed
CN-106093286-A A kind of triazine sulfur elimination sulfur removal effectiveness dynamic evaluation method 西安石油大学 2016-11-09 — — CN claimed
WO-2016145172-A1 WINTERIZING COMPOSITIONS FOR SULFUR SCAVENGERS AND METHODS FOR MAKING AND USING SAME Lubrizol Oilfield Solutions, Inc. (US) 2016-09-15 — — WO claimed
CN-122059553-A Corrosion and scale inhibition sulfur removal agent and preparation method thereof 成都华阳兴华化工有限公司 2026-05-19 — — CN disclosed
CN-122059553-A Corrosion and scale inhibition sulfur removal agent and preparation method thereof 成都华阳兴华化工有限公司 2026-05-19 — — CN disclosed
CN-119912924-B Emulsion type annulus protection liquid and preparation method thereof 新疆科力新技术发展股份有限公司 2026-02-27 — — CN disclosed
US-20250290003-A1 Cluster-Structured, Sulfur Scavenging Composition and Processes for Scavenging Sulfhydryl Moieties in Hydrocarbon Streams THOMPSON JASON MARTIN (US) 2025-09-18 — — US disclosed
CN-117343775-B Method for improving compatibility of triazine sulfur-containing compound and hydraulic transmission oil 中国石油天然气股份有限公司 2025-08-22 — — CN disclosed
EP-0893483-B1 Wet-on-wet primer with low film build U.V. light protection BEE CHEMICAL CO (US) 2003-04-02 — — EP disclosed
US-6034166-A CROSSLINKED MULTILAYER FILM FORMING POLYMER; CONCURRENT CURING BEE CHEMICAL COMPANY (US) 2000-03-07 — — US disclosed
US-5962574-A SPRAYABLE, THERMOSETTING PROTECTIVE COATING; PLASTIC AUTOMOBILE PARTS BEE CHEMICAL COMPANY (US) 1999-10-05 — — US disclosed
EP-0893483-A2 Wet-on-wet primer with low film build U.V. light protection MORTON INTERNATIONAL, INC. (US) 1999-01-27 — — EP disclosed
US-4322214-A USING A SULFUR OR SULFURIZED VAT DYE IN AN ALKALINE BATH CONTAINING A MERCAPTO COMPOUND AND A SULFITE SALT; LEVELING ASAHI CHEMICAL COMPANY LIMITED (JP) 1982-03-30 — — US disclosed
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