SCHEMBL12840364

SCHEMBL12840364

CCCc1nc(-c2ccccc2)cnc1NC(=O)Cc1ccc(F)cc1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.45
WNT3A P56704 5/20 0.44
TMIGD3 P0DMS9 1/20 0.43
NPC1 O15118 2/20 0.43
MEN1 O00255 2/20 0.43
RAB9A P51151 2/20 0.43
LMNA P02545 1/20 0.43
PKM P14618 1/20 0.43
PRKACA P17612 1/20 0.43
ROCK1 Q13464 1/20 0.43
MAPK14 Q16539 2/20 0.42
RORC P51449 1/20 0.41
ELOVL1 Q9BW60 1/20 0.41
GAA P10253 1/20 0.41
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13068038 0.96 MAPK14 (0.46) KMT2AWNT3ATMIGD3NPC1MEN1
SCHEMBL12840473 0.95 KMT2A (0.50) KMT2AWNT3ANPC1MEN1RAB9A
SCHEMBL12840420 0.91 KMT2A (0.47) KMT2AWNT3ANPC1MEN1RAB9A
SCHEMBL12839104 0.91 KMT2A (0.47) KMT2AWNT3ANPC1MEN1RAB9A
SCHEMBL12838993 0.90 TMIGD3 (0.47) KMT2AWNT3ATMIGD3NPC1MEN1
SCHEMBL12840363 0.90 KMT2A (0.46) KMT2AWNT3ATMIGD3NPC1MEN1
SCHEMBL12839069 0.90 KMT2A (0.46) KMT2AWNT3ANPC1MEN1RAB9A
SCHEMBL12840421 0.90 KMT2A (0.46) KMT2AWNT3ANPC1MEN1RAB9A
SCHEMBL12840437 0.90 KMT2A (0.46) KMT2AWNT3ANPC1MEN1RAB9A
SCHEMBL12840474 0.90 KMT2A (0.46) KMT2AWNT3AMEN1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110070656-A1 Fluorescent Proteins JNC CORPORATION (JP) 2011-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110070656-A1 Fluorescent Proteins CACYBP, CHLSN, LCP2 KMT2A 4653/4885WNT3A 510/4885TMIGD3 1782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.