Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 6/20 | 0.45 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.45 |
| ▸ | TET3 | O43151 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | FBXL19 | Q6PCT2 | 3/20 | 0.38 |
| ▸ | CXXC5 | Q7LFL8 | 3/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.38 |
| ▸ | CXXC4 | Q9H2H0 | 3/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.38 |
| ▸ | TET1 | Q8NFU7 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 6/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20892759 | 0.88 | TEAD1 (0.43) | TEAD1TEAD3JAK3JAK1BTK | |
| SCHEMBL17099705 | 0.82 | TEAD1 (0.44) | TEAD1TEAD3TET3KMT2AFBXL19 | |
| SCHEMBL237862 | 0.81 | — | — | |
| SCHEMBL12764449 | 0.81 | TET3 (0.47) | TEAD1TEAD3TET3KMT2AFBXL19 | |
| SCHEMBL167151 | 0.81 | TET3 (0.47) | TEAD1TEAD3TET3KMT2AFBXL19 | |
| SCHEMBL20547259 | 0.81 | TET3 (0.47) | TEAD1TEAD3TET3KMT2AFBXL19 | |
| SCHEMBL29728768 | 0.80 | TEAD1 (0.43) | TEAD1TEAD3TET3KMT2AFBXL19 | |
| SCHEMBL2941527 | 0.80 | TEAD1 (0.43) | TEAD1TEAD3TET3KMT2AFBXL19 | |
| SCHEMBL20780999 | 0.78 | TEAD1 (0.42) | TEAD1TEAD3TET3KMT2AFBXL19 | |
| SCHEMBL12163604 | 0.78 | TEAD1 (0.42) | TEAD1TEAD3TET3KMT2AFBXL19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940425-A | HER2 mutation inhibitors | 阿雷生物药品公司 | 2024-04-26 | — | — | CN | disclosed |
| WO-2011034907-A2 | PROTEIN KINASE CONJUGATES AND INHIBITORS | AVILA THERAPEUTICS, INC. (US) | 2011-03-24 | — | — | WO | disclosed |