Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET3 | O43151 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | FBXL19 | Q6PCT2 | 4/20 | 0.47 |
| ▸ | CXXC5 | Q7LFL8 | 4/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.47 |
| ▸ | CXXC4 | Q9H2H0 | 4/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.47 |
| ▸ | TET1 | Q8NFU7 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.40 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167151 | 1.00 | TET3 (0.47) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL237862 | 1.00 | — | — | |
| SCHEMBL12764449 | 1.00 | TET3 (0.47) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL1591923 | 0.91 | — | — | |
| Vinyl Chloride SCHEMBL11122339 | 0.91 | TET3 (0.43) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL149678 | 0.91 | — | — | |
| SCHEMBL505654 | 0.91 | ALDH1A1 (0.48) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL25231611 | 0.89 | ALDH1A1 (0.55) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL2558338 | 0.89 | ALDH1A1 (0.55) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL329111 | 0.89 | ALDH1A1 (0.55) | TET3KMT2AFBXL19CXXC5KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11241473-B2 | Bicyclic peptide ligands and uses thereof | BICYCLETX LIMITED (GB) | 2022-02-08 | — | — | US | disclosed |
| US-11241473-B2 | Bicyclic peptide ligands and uses thereof | BICYCLETX LIMITED (GB) | 2022-02-08 | — | — | US | disclosed |
| US-20210046145-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | BICYCLETX LIMITED (GB) | 2021-02-18 | — | — | US | disclosed |
| US-20210046145-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | BICYCLETX LIMITED (GB) | 2021-02-18 | — | — | US | disclosed |
| US-10857196-B2 | Bicyclic peptide ligands and uses thereof | BICYCLETX LIMITED (GB) | 2020-12-08 | — | — | US | disclosed |
| US-10857196-B2 | Bicyclic peptide ligands and uses thereof | BICYCLETX LIMITED (GB) | 2020-12-08 | — | — | US | disclosed |
| US-20180311300-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | BICYCLETX LIMITED (GB) | 2018-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10857196-B2 | Bicyclic peptide ligands and uses thereof | VIP, NGLY1, BID | TET3 4803/4885KMT2A 4757/4885FBXL19 3541/4885 |
| US-20180311300-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | VIP, NGLY1, BID | TET3 4803/4885KMT2A 4757/4885FBXL19 3541/4885 |
| US-20210046145-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | VIP, NGLY1, BID | TET3 4803/4885KMT2A 4757/4885FBXL19 3541/4885 |
| US-11241473-B2 | Bicyclic peptide ligands and uses thereof | VIP, NGLY1, BID | TET3 4803/4885KMT2A 4757/4885FBXL19 3541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.