Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17053356 | 0.84 | TRPV4 (0.38) | TRPV4EGLN2PDE4APDE4BPDE4C | |
| SCHEMBL19557560 | 0.82 | CLK4 (0.42) | TRPV4ESR1ESR2EGLN2PDE4A | |
| SCHEMBL30332317 | 0.81 | ESR1 (0.51) | TRPV4ESR1ESR2EGLN2PDE4A | |
| SCHEMBL17244815 | 0.81 | TRPV4 (0.35) | TRPV4EGLN2PDE4APDE4BPDE4C | |
| SCHEMBL15829138 | 0.80 | TRPV4 (0.37) | TRPV4EGLN2PDE4APDE4BPDE4C | |
| SCHEMBL17244817 | 0.79 | HSD17B10 (0.36) | TRPV4EGLN2PDE4APDE4BPDE4C | |
| SCHEMBL19557546 | 0.78 | EGLN2 (0.45) | TRPV4EGLN2CYP11B2CYP11B1 | |
| SCHEMBL9511667 | 0.77 | TRPV4 (0.42) | TRPV4EGLN2S1PR3S1PR1CYP11B2 | |
| SCHEMBL17244816 | 0.77 | TRPV4 (0.34) | TRPV4EGLN2CYP11B2CYP11B1 | |
| SCHEMBL15829133 | 0.76 | RARB (0.38) | TRPV4EGLN2CYP11B2CYP11B1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110075074-A1 | Liquid Crystals Composition and Liquid Crystal Display with Patterned Electrodes | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2011-03-31 | — | — | US | disclosed |