SCHEMBL12840940

SCHEMBL12840940

C=CC(=O)OCCOc1ccc(C(=O)Oc2ccc(S(=O)(=O)c3ccc(OC(=O)c4ccc(OCCOC(=O)C=C)cc4F)cc3)cc2)c(F)c1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.45
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
LSS P48449 1/20 0.35
CRBN Q96SW2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAOB P27338 1/20 0.33
ELANE P08246 1/20 0.33
GAA P10253 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
KAT6A Q92794 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12840939 0.95 THRB (0.39) THRBPOLBMAPTPKMMEN1
SCHEMBL16425358 0.94 TSHR (0.40) THRBPOLBMAPTPKMMEN1
SCHEMBL13962708 0.94 TSHR (0.40) THRBPOLBMAPTPKMMEN1
SCHEMBL13828876 0.92 THRB (0.52) THRBMEN1KMT2ALSSCRBN
SCHEMBL12769672 0.92 THRB (0.38) THRBPOLBMAPTPKMMEN1
SCHEMBL14026827 0.91 HPGD (0.43) THRBMEN1KMT2ALSSCRBN
SCHEMBL11986152 0.90 POLB (0.36) THRBPOLBMAPTPKMKMT2A
SCHEMBL14117072 0.90 POLB (0.44) THRBPOLBMAPTPKMMEN1
SCHEMBL12769659 0.89 POLB (0.43) THRBPOLBMAPTPKMMEN1
SCHEMBL12769660 0.89 POLB (0.43) THRBPOLBMAPTPKMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9080100-B2 Polymerizable liquid crystal composition JNC CORPORATION (JP) 2015-07-14 US disclosed
US-9080100-B2 Polymerizable liquid crystal composition JNC CORPORATION (JP) 2015-07-14 US disclosed
US-20150029446-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICAL ANISOTROPIC FILM JNC PETROCHEMICAL CORPORATION (JP) 2015-01-29 US disclosed
US-20150029446-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICAL ANISOTROPIC FILM JNC PETROCHEMICAL CORPORATION (JP) 2015-01-29 US disclosed
US-RE42221-E1 Polymerizable liquid crystal composition and polymer thereof CHISSO CORPORATION (JP) 2011-03-15 US disclosed
US-7488519-B2 Polymerizable liquid crystal composition CHISSO CORPORATION (JP) 2009-02-10 US disclosed
US-7488519-B2 Polymerizable liquid crystal composition CHISSO CORPORATION (JP) 2009-02-10 US disclosed
US-7476423-B2 Polymerizable liquid crystal composition CHISSO CORPORATION (JP) 2009-01-13 US disclosed
US-7476423-B2 Polymerizable liquid crystal composition CHISSO CORPORATION (JP) 2009-01-13 US disclosed
US-20080241431-A1 Polymerizable liquid crystal composition CHISSO CORPORATION 2008-10-02 US disclosed
US-20080241431-A1 Polymerizable liquid crystal composition CHISSO CORPORATION 2008-10-02 US disclosed
US-7393569-B2 Hexafluoroisopropylidenebis- and sulfonylbis-(phenoxycarbonylphenoxyalkyl acrylates); hexafluoroisopropylidenebis- and sulfonylbis-(phenoxycarbonylphenoxyalkyloxetanes; stabilizes polymerizable liquid crystal compositions for a long time and controls the alignment of liquid crystal molecules CHISSO CORPORATION (JP) 2008-07-01 US disclosed
US-7393569-B2 Hexafluoroisopropylidenebis- and sulfonylbis-(phenoxycarbonylphenoxyalkyl acrylates); hexafluoroisopropylidenebis- and sulfonylbis-(phenoxycarbonylphenoxyalkyloxetanes; stabilizes polymerizable liquid crystal compositions for a long time and controls the alignment of liquid crystal molecules CHISSO CORPORATION (JP) 2008-07-01 US disclosed
US-20080014374-A1 Polymerizable liquid crystal composition JNC PETROCHEMICAL CORPORATION (JP) 2008-01-17 US disclosed
US-20080014374-A1 Polymerizable liquid crystal composition JNC PETROCHEMICAL CORPORATION (JP) 2008-01-17 US disclosed