Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 2/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA5A | P35218 | 4/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17779170 | 1.00 | KMT2A (0.59) | KMT2AALDH1A1MEN1LMNAMAPT | |
| SCHEMBL6126355 | 1.00 | KMT2A (0.59) | KMT2AALDH1A1MEN1LMNAMAPT | |
| SCHEMBL20254178 | 1.00 | KMT2A (0.59) | KMT2AALDH1A1MEN1LMNAMAPT | |
| SCHEMBL107676 | 1.00 | KMT2A (0.59) | KMT2AALDH1A1MEN1LMNAMAPT | |
| SCHEMBL411430 | 1.00 | KMT2A (0.59) | KMT2AALDH1A1MEN1LMNAMAPT | |
| SCHEMBL15492870 | 1.00 | KMT2A (0.59) | KMT2AALDH1A1MEN1LMNAMAPT | |
| SCHEMBL27669444 | 0.86 | KMT2A (0.61) | KMT2AALDH1A1MEN1LMNAMAPT | |
| SCHEMBL15681900 | 0.85 | KMT2A (0.56) | KMT2AALDH1A1MEN1LMNAMAPT | |
| Benzidine SCHEMBL29172643 | 0.85 | KMT2A (0.47) | KMT2AALDH1A1MEN1LMNAF2 | |
| SCHEMBL13761872 | 0.83 | KMT2A (0.58) | KMT2AALDH1A1MEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292596-A2 | CETP activity inhibitor | Japan Tobacco, Inc. (JP) | 2011-03-09 | — | — | EP | disclosed |