SCHEMBL128442

SCHEMBL128442

CCCCCCCCCCCCCCC[NH]

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.61
THRB P10828 1/20 0.61
DNM1 Q05193 7/20 0.44
ALDH1A1 P00352 3/20 0.44
LMNA P02545 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HSD17B10 Q99714 1/20 0.44
SLC22A1 O15245 1/20 0.44
EPHX1 P07099 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7072895 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL129696 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL197417 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL6385316 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL129402 1.00
SCHEMBL130979 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL6387311 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL49384 1.00
SCHEMBL131525 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL6387586 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240009230-A1 PT(IV) CHEMOTHERAPEUTIC PRODRUG AND CONTROLLED RELEASE THEREOF FOR TREATMENT OF TUMORS PEKING UNIVERSITY (CN) 2024-01-11 US claimed
EP-4253392-A1 PT(IV) CHEMOTHERAPEUTIC PRODRUG AND CONTROLLED RELEASE THEREOF FOR TREATMENT OF TUMORS Peking University (CN) 2023-10-04 EP claimed
CN-116635396-A Pt (IV) chemotherapeutic prodrugs and their controlled release for treating tumors 北京大学 2023-08-22 CN claimed
US-20240092810-A1 COMPOSITIONS FOR EXTREME ULTRAVIOLET LITHOGRAPHY AND RELATED METHODS ENTEGRIS, INC. 2024-03-21 US disclosed
WO-2024049919-A1 COMPOSITIONS FOR EXTREME ULTRAVIOLET LITHOGRAPHY AND RELATED METHODS ENTEGRIS, INC. (US) 2024-03-07 WO disclosed
US-20240009230-A1 PT(IV) CHEMOTHERAPEUTIC PRODRUG AND CONTROLLED RELEASE THEREOF FOR TREATMENT OF TUMORS PEKING UNIVERSITY (CN) 2024-01-11 US disclosed
EP-4253392-A1 PT(IV) CHEMOTHERAPEUTIC PRODRUG AND CONTROLLED RELEASE THEREOF FOR TREATMENT OF TUMORS Peking University (CN) 2023-10-04 EP disclosed
WO-2023176796-A1 SCAR FORMATION INHIBITOR, FIBROBLAST PROLIFERATION INHIBITOR, AND METHOD FOR PRODUCING NANOPARTICLES 国立大学法人東北大学 2023-09-21 WO disclosed
CN-116635396-A Pt (IV) chemotherapeutic prodrugs and their controlled release for treating tumors 北京大学 2023-08-22 CN disclosed
CN-116099978-A Three-component amine method cold box binder 济南圣泉集团股份有限公司 2023-05-12 CN disclosed
EP-3689891-B1 COBALT COMPLEX, PRODUCTION METHOD THEREFOR, AND CATALYST FOR HYDROSILYLATION REACTION UNIV KYUSHU NAT UNIV CORP (JP) 2023-03-01 EP disclosed
US-5064962-A DIAMINOTHIOPHENES BASF AKTIENGESELLSCHAFT (DE) 1991-11-12 US disclosed
EP-0433879-A2 Aminothiazoles BASF Aktiengesellschaft (DE) 1991-06-26 EP disclosed
EP-0421441-A2 Pantothenic acid derivatives FUJIREBIO INC. (JP) 1991-04-10 EP disclosed
EP-0384314-A2 Diaminothiophenes BASF Aktiengesellschaft (DE) 1990-08-29 EP disclosed
EP-0159913-B1 SILVER HALIDE PHOTOGRAPHIC LIGHT SENSITIVE MATERIAL KONICA CORPORATION (JP) 1988-09-14 EP disclosed
EP-0094804-B1 GLUCOSAMINYL MURAMYL PEPTIDE DERIVATIVES Dainippon Pharmaceutical Co., Ltd. (JP) 1985-11-13 EP disclosed
EP-0159913-A1 Silver halide photographic light sensitive material KONICA CORPORATION (JP) 1985-10-30 EP disclosed
US-4545932-A NONSPECIFIC RESISTANCE TO MICROBIAL INFECTIONS, IMMUNOSTIMULANTS DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1985-10-08 US disclosed
EP-0094804-A1 Glucosaminyl muramyl peptide derivatives Dainippon Pharmaceutical Co., Ltd. (JP) 1983-11-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240092810-A1 COMPOSITIONS FOR EXTREME ULTRAVIOLET LITHOGRAPHY AND RELATED METHODS ALG3, VCL, ETV6 TSHR 3896/4885THRB 3319/4885DNM1 1449/4885
US-20240009230-A1 PT(IV) CHEMOTHERAPEUTIC PRODRUG AND CONTROLLED RELEASE THEREOF FOR TREATMENT OF TUMORS TK1, TYMP, KIT TSHR 833/4885THRB 941/4885DNM1 4723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.