Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 11/20 | 0.67 |
| ▸ | THRA | P10827 | 8/20 | 0.67 |
| ▸ | PPARG | P37231 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | TTR | P02766 | 2/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | RXRA | P19793 | 2/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.67 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | HTR1A | P08908 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.67 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.67 |
| ▸ | HTR2B | P41595 | 1/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468893 | 0.91 | THRB (0.69) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL28626300 | 0.91 | THRB (0.65) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL468892 | 0.91 | THRB (0.69) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL11190023 | 0.90 | THRB (0.64) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL11190025 | 0.90 | THRB (0.64) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL13949745 | 0.90 | THRB (0.64) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL8244912 | 0.89 | THRB (0.66) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL5152662 | 0.89 | THRB (0.62) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL5152656 | 0.89 | THRB (0.62) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL17612148 | 0.88 | THRB (0.68) | THRBTHRAPPARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10267775-B2 | Extraction, derivatization, and quantification of analytes | TECAN SP, INC. (US) | 2019-04-23 | — | — | US | disclosed |
| US-20150346170-A1 | Extraction, Derivatization, and Quantification of Analytes | QUANTALYTICAL LABS INC. (US) | 2015-12-03 | — | — | US | disclosed |
| US-20150346170-A1 | Extraction, Derivatization, and Quantification of Analytes | QUANTALYTICAL LABS INC. (US) | 2015-12-03 | — | — | US | disclosed |
| WO-2010148007-A9 | NANOPARTICLE AND POLYMER FORMULATIONS FOR THYROID HORMONE, ANALOGS, ANTAGONISTS, AND FORMULATIONS AND USES THEREOF | ORDWAY RESEARCH INSTITUTE, INC. (US) | 2011-03-24 | — | — | WO | disclosed |
| WO-2010148007-A2 | NANOPARTICLE AND POLYMER FORMULATIONS FOR THYROID HORMONE, ANALOGS, ANTAGONISTS, AND FORMULATIONS AND USES THEREOF | ORDWAY RESEARCH INSTITUTE, INC. (US) | 2010-12-23 | — | — | WO | disclosed |