Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8363702 | 0.89 | F10 (0.46) | F10PTGS2 | |
| SCHEMBL12844833 | 0.89 | F10 (0.55) | F10PTGS2 | |
| SCHEMBL12844501 | 0.87 | F10 (0.53) | F10PTGS2 | |
| SCHEMBL12777475 | 0.84 | F10 (0.51) | F10PTGS2 | |
| SCHEMBL12777476 | 0.83 | F10 (0.51) | F10PTGS2 | |
| SCHEMBL2071592 | 0.80 | PTGS2 (0.50) | F10PTGS2 | |
| SCHEMBL2072679 | 0.80 | PTGS2 (0.50) | F10PTGS2 | |
| SCHEMBL2072796 | 0.79 | F10 (0.51) | F10PTGS2 | |
| SCHEMBL2071548 | 0.79 | F10 (0.49) | F10PTGS2 | |
| SCHEMBL2073183 | 0.79 | F10 (0.51) | F10PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902223-B2 | For therapy and prophylaxis of thromboses, myocardial infarction, arteriosclerosis, inflammation, apoplexia, angina pectoris, restenosis after angioplasty, claudicatio intermittens, migraine, tumours, tumour diseases and/or tumour metastases | MERCK PATENT GMBH (DE) | 2011-03-08 | — | — | US | disclosed |