Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 2/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352852 | 0.78 | FABP6 (0.60) | FABP6PKMTSHRKEAP1ITGB2 | |
| SCHEMBL29463796 | 0.78 | FABP6 (0.60) | FABP6PKMTSHRKEAP1ITGB2 | |
| Hydrochloric Acid SCHEMBL29731561 | 0.76 | FABP6 (0.58) | FABP6PKMTSHRKEAP1ITGB2 | |
| SCHEMBL14477816 | 0.70 | ITGB2 (0.39) | FABP6PKMTSHRKEAP1ITGB2 | |
| SCHEMBL10904842 | 0.70 | ADRA2A (0.41) | KEAP1ITGB2ICAM1ITGALLMNA | |
| SCHEMBL23196172 | 0.68 | FABP6 (0.49) | FABP6PKMTSHRKEAP1ITGB2 | |
| SCHEMBL30094694 | 0.67 | ITGB2 (0.48) | FABP6KEAP1ITGB2ICAM1ITGAL | |
| SCHEMBL11343714 | 0.67 | ITGB2 (0.59) | PKMTSHRITGB2ICAM1ITGAL | |
| SCHEMBL10025838 | 0.66 | ITGB2 (0.46) | PKMTSHRITGB2ICAM1ITGAL | |
| SCHEMBL12446304 | 0.66 | ITGB2 (0.57) | PKMTSHRITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034051-A1 | NOVEL CYCLIC SQUARAMIDE DERIVATIVES | 参天製薬株式会社 (JP) | 2011-03-24 | — | — | WO | disclosed |