SCHEMBL128500

SCHEMBL128500

CCCCC(CC)Cc1cccc(C(=O)O)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
CA2 P00918 1/20 0.48
CYP3A4 P08684 1/20 0.48
LMNA P02545 1/20 0.47
HMGB1 P09429 1/20 0.47
PRSS1 P07477 1/20 0.43
PRSS2 P07478 1/20 0.43
PRSS3 P35030 1/20 0.43
KDM4E B2RXH2 3/20 0.41
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.41
GLA P06280 1/20 0.40
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
BID P55957 3/20 0.40
MCL1 Q07820 3/20 0.40
BCL2L1 Q07817 2/20 0.40
BAK1 Q16611 2/20 0.40
KAT8 Q9H7Z6 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6265206 0.90 ALDH1A1 (0.47) ALDH1A1CA2CYP3A4LMNAHMGB1
SCHEMBL10782179 0.88 HMGB1 (0.54) ALDH1A1CYP3A4LMNAHMGB1KDM4E
SCHEMBL9517619 0.88 ALDH1A1 (0.47) ALDH1A1CA2CYP3A4LMNAPRSS1
SCHEMBL11338154 0.88 HMGB1 (0.52) ALDH1A1CA2CYP3A4LMNAHMGB1
SCHEMBL31073993 0.87 ALDH1A1 (0.55) ALDH1A1CA2CYP3A4LMNAPRSS1
SCHEMBL131266 0.87 ALDH1A1 (0.55) ALDH1A1CA2CYP3A4LMNAPRSS1
SCHEMBL2348289 0.86 ALDH1A1 (0.48) ALDH1A1CA2CYP3A4LMNAPRSS1
SCHEMBL21114417 0.86 ALDH1A1 (0.48) ALDH1A1CA2CYP3A4LMNAPRSS1
SCHEMBL29672612 0.86 ALDH1A1 (0.48) ALDH1A1CA2CYP3A4LMNAPRSS1
SCHEMBL7165074 0.86 ALDH1A1 (0.48) ALDH1A1CA2CYP3A4LMNAPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3410 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260130837-A1 SPF BOOSTER AND SUNCARE FORMULATIONS INCLUDING SAME DOW SILICONES CORP (US) 2026-05-14 US claimed
US-12622861-B2 Stable wash composition CONOPCO, INC. (US) 2026-05-12 US claimed
EP-4061326-B1 PERSONAL CARE COMPOSITION COMPRISING A MULTISTAGE POLYMER DOW GLOBAL TECHNOLOGIES LLC (US) 2026-02-25 EP claimed
US-12514802-B2 Polymer/hydrophobic ester oil blend DOW SILICONES CORPORATION (US) 2026-01-06 US claimed
WO-2025262042-A1 SILANE-MODIFIED POLYMER COMPOSITION WITH ENHANCED STABILITY PROPERTIES HENKEL AG & CO. KGAA (DE) 2025-12-26 WO claimed
US-12409117-B2 Wash composition substantially free of oil CONOPCO, INC. (US) 2025-09-09 US claimed
EP-4093514-B1 AQUEOUS SUNCASE FORMULATION BASED ON SULFATED A CRYSTALLINE CELLULOSE SPF BOOSTER DOW GLOBAL TECHNOLOGIES LLC (US) 2025-08-06 EP claimed
EP-4590261-A1 SUN CARE FORMULATION Rohm and Haas Company (US) 2025-07-30 EP claimed
EP-4590260-A1 SPF BOOSTER AND SUNCARE FORMULATIONS INCLUDING SAME Dow Silicones Corporation (US) 2025-07-30 EP claimed
US-12370134-B2 Personal care formulation DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-29 US claimed
EP-0552289-A4 PREVENTION OR TREATMENT OF SUNBURN USING THE S(+) ISOMER OF KETOPROFEN 1993-08-11 EP claimed
EP-0552289-A1 PREVENTION OR TREATMENT OF SUNBURN USING THE S(+) ISOMER OF KETOPROFEN MILES INC. (US) 1993-07-28 EP claimed
EP-0503922-A2 Cosmetics having photoprotection properties MAX FACTOR K.K. (JP) 1992-09-16 EP claimed
EP-0376821-B1 COMPOSITIONS FOR INDUCING AND STIMULATING HAIR GROWTH AND/OR STOP THEIR FALL BASED ON PYRIMIDINE DERIVATIVES AND UV FILTERS L'OREAL (FR) 1992-08-26 EP claimed
WO-1992005769-A1 PREVENTION OR TREATMENT OF SUNBURN USING THE S(+) ISOMER OF KETOPROFEN MILES, INC. (US) 1992-04-16 WO claimed
WO-1992005768-A1 PREVENTION OR TREATMENT OF SUNBURN USING THE S(+) ISOMER OF FLURBIPROFEN ANALGESIC ASSOCIATES (US) 1992-04-16 WO claimed
US-5100918-A Prevention or treatment of sunburn using the S(+) isomer of ibuprofen STERLING DRUG, INC. (US) 1992-03-31 US claimed
WO-1991017740-A1 PREVENTION OR TREATMENT OF SUNBURN USING THE S(+) ISOMER OF FLURBIPROFEN ANALGESIC ASSOCIATES (US) 1991-11-28 WO claimed
EP-0261812-B1 COSMETIC COMPOSITION UNILEVER PLC (GB) 1991-08-14 EP claimed
US-4150114-A ENHANCED PENETRATION THE PROCTER & GAMBLE COMPANY (US) 1979-04-17 US claimed