⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL28173806 | 0.91 | — | — | |
| Formaldehyde SCHEMBL6009683 | 0.89 | — | — | |
| Formaldehyde SCHEMBL9298240 | 0.89 | — | — | |
| Formaldehyde SCHEMBL14312024 | 0.89 | — | — | |
| Formaldehyde SCHEMBL4350563 | 0.89 | — | — | |
| Formaldehyde SCHEMBL157950 | 0.89 | — | — | |
| Formaldehyde SCHEMBL6840 | 0.89 | — | — | |
| Formaldehyde SCHEMBL25244636 | 0.80 | — | — | |
| Formaldehyde SCHEMBL19547832 | 0.80 | — | — | |
| Formaldehyde SCHEMBL8975297 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105862-A | Donepezil hydrochloride impurity and preparation method thereof | 浙江华海药业股份有限公司 | 2022-03-01 | — | — | CN | claimed |
| CN-105646216-A | Synthesis method of 2-fluoro-methyl 3-hydroxypropionate | 湖北工程学院 | 2016-06-08 | — | — | CN | claimed |
| CN-114369080-B | Device and method for synthesizing ethylene carbonate or propylene carbonate | 凯瑞环保科技股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-114437014-B | Device and method for synthesizing ethylene carbonate or propylene carbonate | 凯瑞环保科技股份有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-114105862-A | Donepezil hydrochloride impurity and preparation method thereof | 浙江华海药业股份有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-113166393-A | Method for preparing polyoxyethylene 1, 4-sorbitan fatty acid ester | 广州龙沙制药有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-105646216-B | The hydroxy methyl propionate synthetic method of 2 fluorine 3 | 湖北工程学院 | 2018-04-03 | — | — | CN | disclosed |
| CN-105646216-A | Synthesis method of 2-fluoro-methyl 3-hydroxypropionate | 湖北工程学院 | 2016-06-08 | — | — | CN | disclosed |
| CN-105263894-A | Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof | SYNGENTA LTD | 2016-01-20 | — | — | CN | disclosed |
| EP-1861359-B1 | N-(N-SULFONYLAMINOMETHYL)CYCLOPROPANECARBOXAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF PAIN | PFIZER (US) | 2012-11-14 | — | — | EP | disclosed |
| US-20120088746-A1 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | PFIZER INC. (US) | 2012-04-12 | — | — | US | disclosed |
| EP-2024272-A2 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | Renovis, Inc. (US) | 2009-02-18 | — | — | EP | disclosed |
| WO-2008090434-A1 | SUBSTITUTED N-BICYCLICALKYL BICYCLIC CARBOXYAMIDE COMPOUNDS | PFIZER JAPAN INC. (JP) | 2008-07-31 | — | — | WO | disclosed |
| EP-1866278-A1 | SUBSTITUTED ARYLOXOETHYL CYCLOPROPANECARBOXAMIDE COMPOUNDS AS VR1 RECEPTOR ANTAGONISTS | Pfizer, Inc. (US) | 2007-12-19 | — | — | EP | disclosed |
| EP-1861359-A1 | N-(N-SULFONYLAMINOMETHYL)CYCLOPROPANECARBOXAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF PAIN | Pfizer, Inc. (US) | 2007-12-05 | — | — | EP | disclosed |
| WO-2007133637-A2 | AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME | RENOVIS, INC. (US) | 2007-11-22 | — | — | WO | disclosed |
| WO-2006097817-A9 | N- (N-SULFONYLAMINOMETHYL) CYCLOPROPANECARBOXAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF PAIN | PFIZER JAPAN INC (JP) | 2006-12-07 | — | — | WO | disclosed |
| WO-2006103503-A1 | SUBSTITUTED ARYLOXOETHYL CYCLOPROPANECARBOXAMIDE COMPOUNDS AS VR1 RECEPTOR ANTAGONISTS | PFIZER JAPAN INC. (JP) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006097817-A1 | N- (N-SULFONYLAMINOMETHYL) CYCLOPROPANECARBOXAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF PAIN | PFIZER JAPAN INC. (JP) | 2006-09-21 | — | — | WO | disclosed |
| US-20060211741-A1 | Substituted sulfonylaminoarylmethyl cyclopropanecarboxamide as VR1 receptor antagonists | PFIZER, INC. | 2006-09-21 | — | — | US | disclosed |