⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL14312024 | 0.89 | — | — | |
| Formaldehyde SCHEMBL6009683 | 0.89 | — | — | |
| Formaldehyde SCHEMBL157950 | 0.89 | — | — | |
| Formaldehyde SCHEMBL28610918 | 0.89 | — | — | |
| Formaldehyde SCHEMBL25244636 | 0.80 | — | — | |
| Formaldehyde SCHEMBL19547832 | 0.80 | — | — | |
| Formaldehyde SCHEMBL1285463 | 0.80 | — | — | |
| Formaldehyde SCHEMBL1453233 | 0.80 | — | — | |
| Formaldehyde SCHEMBL10418319 | 0.80 | — | — | |
| Formaldehyde SCHEMBL5141658 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102653542-B | Synthetic method of narcotine | UNIV SHENYANG PHARMACEUTICAL | 2014-12-17 | — | — | CN | claimed |
| CN-114957257-A | Preparation method of calcium 5-methyltetrahydrofolate | 河北冀衡药业股份有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-108164531-B | A kind of preparation method of L-5- methyl tetrahydrofolate calcium | 江苏红豆杉药业有限公司 | 2019-11-05 | — | — | CN | disclosed |
| CN-108164531-A | A kind of preparation method of L-5- methyl tetrahydrofolates calcium | 江苏红豆杉药业有限公司 | 2018-06-15 | — | — | CN | disclosed |
| CN-102653542-B | Synthetic method of narcotine | UNIV SHENYANG PHARMACEUTICAL | 2014-12-17 | — | — | CN | disclosed |
| WO-2013111161-A2 | PROCESS FOR THE PREPARATION OF 3-ARYL-2-METHYL-PROPANAMINE DERIVATIVES AND POLYMORPHS THEREOF | MSN LABORATORIES LIMITED (IN) | 2013-08-01 | — | — | WO | disclosed |
| US-5571921-A | AMINATION OF PIPERIDINE DERIVATIVES BY DEHYDROHALOGENATION | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-05 | — | — | US | disclosed |
| US-5492918-A | Use of substituted chromans, some of which are known, as medicaments, new active compounds and processes for their preparation | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-20 | — | — | US | disclosed |
| CN-1097745-A | The piperazine that replaces | BAYER AG (DE) | 1995-01-25 | — | — | CN | disclosed |