Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 6/20 | 0.48 |
| ▸ | CTSS | P25774 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31758034 | 0.91 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL9596442 | 0.89 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL15374288 | 0.89 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL25008491 | 0.89 | CTSK (0.49) | CYP1A2CYP2C9CYP2C19HTTCTSK | |
| SCHEMBL15107084 | 0.89 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL12069015 | 0.87 | CYP1A2 (0.64) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL12071191 | 0.87 | CYP1A2 (0.64) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL12070120 | 0.87 | CYP1A2 (0.64) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL20467854 | 0.84 | CYP1A2 (0.58) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL27687476 | 0.84 | CYP1A2 (0.58) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120276600-A1 | Process For Preparing Dipeptidyl Peptidase IV Inhibitors And Intermediates Therefor | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-11-01 | — | — | US | disclosed |
| EP-2517706-A2 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | Bristol-Myers Squibb Company (US) | 2012-10-31 | — | — | EP | disclosed |
| US-8278462-B2 | Methods and compounds for producing dipeptidyl peptidase IV inhibitors and intermediates thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-10-02 | — | — | US | disclosed |
| US-20100274025-A1 | METHODS AND COMPOUNDS FOR PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100274025-A1 | METHODS AND COMPOUNDS FOR PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | DPP4, DPP3, DPP8 | CYP1A2 1863/4885CYP2C9 615/4885CYP2C19 1145/4885 |
| US-20120276600-A1 | Process For Preparing Dipeptidyl Peptidase IV Inhibitors And Intermediates Therefor | DNPEP, DPP4, DPP8 | CYP1A2 3244/4885CYP2C9 1957/4885CYP2C19 1933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.