SCHEMBL128554

SCHEMBL128554

[CH2]CCCCOCCCC

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
MEN1 O00255 1/20 0.46
THRB P10828 1/20 0.46
HTT P42858 1/20 0.46
KMT2A Q03164 1/20 0.46
MAPT P10636 1/20 0.46
CYP3A4 P08684 1/20 0.44
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
ADRB3 P13945 1/20 0.39
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
CES2 O00748 1/20 0.38
HPGD P15428 1/20 0.38
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
USP2 O75604 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL130731 0.97 TSHR (0.50) TSHRMEN1THRBHTTKMT2A
SCHEMBL816285 0.97 TSHR (0.50) TSHRMEN1THRBHTTKMT2A
SCHEMBL820419 0.97 TSHR (0.50) TSHRMEN1THRBHTTKMT2A
SCHEMBL816419 0.97 TSHR (0.50) TSHRMEN1THRBHTTKMT2A
SCHEMBL816971 0.97 TSHR (0.50) TSHRMEN1THRBHTTKMT2A
SCHEMBL818096 0.97 TSHR (0.50) TSHRMEN1THRBHTTKMT2A
SCHEMBL816279 0.97 TSHR (0.50) TSHRMEN1THRBHTTKMT2A
SCHEMBL815974 0.97 TSHR (0.50) TSHRMEN1THRBHTTKMT2A
SCHEMBL816140 0.97 TSHR (0.50) TSHRMEN1THRBHTTKMT2A
SCHEMBL817599 0.97 TSHR (0.50) TSHRMEN1THRBHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 596 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024089310-A1 BIODEGRADABLE IMINOSUGARS AND AMINO CYCLITOL GLYCOSIDES INHIBITING ALPHA-GLUCOSIDASE WITH SYNERGISTIC INSECTICIDE OR ACARICIDE ACTIVITY OR BOTH FRANCISCO ARAGÓN S.L.U (ES) 2024-05-02 WO claimed
EP-2890756-A1 RESIN-BASED SEALANT COMPOSITIONS COMPRISING CEMENT KILN DUST AND METHODS OF USE Halliburton Energy Services, Inc. (US) 2015-07-08 EP claimed
WO-2014036218-A1 RESIN-BASED SEALANT COMPOSITIONS COMPRISING CEMENT KILN DUST AND METHODS OF USE HALLIBURTON ENERGY SERVICES, INC. (US) 2014-03-06 WO claimed
US-7786332-B2 Process for the preparation of ring compounds MERCK PATENT GMBH (DE) 2010-08-31 US claimed
US-7429393-B2 Graft polymer BRIDGESTONE CORPORATION (JP) 2008-09-30 US claimed
EP-1654225-A4 MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONISTS AMGEN INC (US) 2007-11-28 EP claimed
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US claimed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP claimed
EP-1654225-A2 MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONISTS Amgen, Inc. (US) 2006-05-10 EP claimed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US claimed
US-20010021743-A1 Method of producing a graft copolymer BRIDGESTONE CORPORATION (JP) 2001-09-13 US claimed
US-6207763-B1 A COPOLYMER OF SUBSTITUTED OR UNSUBSTITUTED 1-20 ALKYL GROUP DISUBSTITUTED ETHYLENE-MALEIMIDE COPOLYMER(A REACTION PRODUCT OF DISUBTITUTED ETHYLENE-MALEIC ANHYDRIDE IMIDIZED WITH PRIMARY AMINE) IS A PLASTICIZER FOR RUBBER; HIGH DAMPING BRIDGESTONE CORPORATION (JP) 2001-03-27 US claimed
US-6204354-B1 DRY ENVIRONMENT BRIDGESTONE CORPORATION (JP) 2001-03-20 US claimed
US-6191217-B1 REACTING POLY(ALKYL VINYLETHER-CO-MALEIMIDE) POLYMER WITH MALEATED POLYALKYLENE AND ALKYL DIAMINE UNDER SUBSTANTIALLY DRY CONDITIONS SUFFICIENT TO FORM POLYALKYLENE GRAFTED POLY(ALKYL VINYLETHER-CO-MALEIMIDE) POLYMER BRIDGESTONE CORPORATION (JP) 2001-02-20 US claimed
US-6133354-A MIXING A POLY(DIALKYLSUBSTITUTED ETHYLENE-CO-MALEIMIDE) POLYMER SUCH AS POLYISOBUTYLENE-CO-MALEIMIDE, AND PLASTICIZERS OR EXTENDERS WITHIN A NON-VULCANIZED THERMOPLASTIC ELASTOMER TO FORM A DAMPING GEL; TENSILE STRENGTH AND TEAR STRENGTH BRIDGESTONE CORPORATION (JP) 2000-10-17 US claimed
EP-0955319-A1 Soft compounds derived from polypropylene grafted disubstituted ethylene-maleimide copolymers Bridgestone Corporation (JP) 1999-11-10 EP claimed
US-5190689-A Polymer materials having liquid-crystalline phases MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-03-02 US claimed
US-4894181-A Carbocyclic compounds MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1990-01-16 US claimed
US-4758373-A Carbocyclic compounds MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-07-19 US claimed
US-4648898-A DIAMINO-DIFLUOROMETHYLTHIOTRIAZINES SHIONOGI & CO., LTD. (JP) 1987-03-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 TSHR 4680/4885MEN1 3377/4885THRB 3757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.