Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 4/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 11/20 | 0.41 |
| ▸ | LDHA | P00338 | 5/20 | 0.41 |
| ▸ | LDHB | P07195 | 5/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.41 |
| ▸ | BCL2 | P10415 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22700788 | 0.80 | MCL1 (0.61) | ALBAKR1B1LDHALDHBMCL1 | |
| SCHEMBL2622254 | 0.72 | AKR1B1 (0.46) | ALBAKR1B1LDHALDHBMCL1 | |
| SCHEMBL2622261 | 0.66 | ALB (0.53) | ALBAKR1B1LDHALDHBMCL1 | |
| SCHEMBL2622242 | 0.63 | AKR1B1 (0.39) | ALBAKR1B1LDHALDHBMCL1 | |
| SCHEMBL2622255 | 0.62 | ALB (0.51) | ALBAKR1B1LDHALDHBMCL1 | |
| SCHEMBL2622252 | 0.62 | AKR1B1 (0.64) | ALBAKR1B1LDHALDHBMCL1 | |
| SCHEMBL10268835 | 0.62 | AKR1B1 (0.51) | ALBAKR1B1LDHALDHBMCL1 | |
| SCHEMBL2622247 | 0.61 | ALB (0.63) | ALBAKR1B1LDHALDHBMCL1 | |
| SCHEMBL2622251 | 0.60 | AKR1B1 (0.71) | ALBAKR1B1LDHALDHBMCL1 | |
| SCHEMBL13196653 | 0.60 | MCL1 (0.81) | ALBAKR1B1LDHALDHBMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046233-A1 | GOSSYPOL DERIVATIVES, PRODUCTION METHOD THEREOF AND USES OF SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-02-24 | — | — | US | disclosed |
| US-7851510-B2 | protein kinase inhibitors such as 6,7,6',7'-tetrahydroxy-8,8'-bis-methoxymethyl-5,5'-diisopropyl-3,3'-dimethyl-[2,2']binaphthalenyl-1,4,1',4'-tetraone, used in the treatment of melanomas, glioblastomas, adenocarcinomas, colon, lung, prostate or breast cancers | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2010-12-14 | — | — | US | disclosed |
| US-20090318566-A1 | GOSSYPOL DERIVATIVES, PRODUCTION METHOD THEREOF AND USES OF SAME | MICHELOT, ROBERT, MR. (FR) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046233-A1 | GOSSYPOL DERIVATIVES, PRODUCTION METHOD THEREOF AND USES OF SAME | GGPS1, CYP11B1, CYP11B2 | ALB 4167/4885AKR1B1 67/4885LDHA 3642/4885 |
| US-20090318566-A1 | GOSSYPOL DERIVATIVES, PRODUCTION METHOD THEREOF AND USES OF SAME | GGPS1, CYP11B1, CYP11B2 | ALB 4167/4885AKR1B1 67/4885LDHA 3642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.